The relative influence of the topography and chemistry of TiAl6V4 surfaces on osteoblastic cell behaviour

Surface Properties and Biocompatibility of Acid-etched Titanium

“…In the same vein, there were some studies which reported that there were no clear effects of surface roughness on proliferation of bone cells [27][28][29] . However, other studies reported a significant correlation between surface roughness and cell growth, whereby greater proliferation of osteoblasts on smoother or rougher surfaces resulted in better ossteointegration [30][31][32][33][34] . Currently, we have no clear explanation for this discrepancy.…”

Influencia del arenado de la aleación Ti6Al4V en la dureza subsuperficial y estado de tensiones residuales

“…Uno de los métodos más utilizados para mejorar la osteointegración del implante consiste en un tratamiento de arenado con partículas de alúmina o silicatos cuyo tamaño, forma y energía cinética condicionan fuertemente la rugosidad. El arenado cambia la composición de la superficie [1][2][3] , aunque la presencia de las partículas residuales no parece tener un efecto en la osteointegración [4] . Datos obtenidos in vivo han puesto de manifiesto que las superficies rugosas producen una fijación mecánica u osteointegración mejor que la correspondiente a superficies lisas [5][6][7] .…”

Characterization and Evaluation of Surface Modified Titanium Alloy by Pulse Nd:YAG Laser for Orthopaedic Applications: an Invivo Study

“…Ligands are the junctions which facilitate adhesion of bone cells to implant surface. In another word, more ligand formation implies a better cell-surface interaction [Tirrell et al, 2002;Anselme et al, 2000]. In vitro studies can be used to study the influence of surface properties on processes such as cell attachment, cell proliferation and cell differentiation.…”