The relative in vitro responsiveness of melanophores of winter flounder to α‐MSH and MCH

Abstract

Melanin-concentrating hormone (MCH) was more potent than the antagonistic melanophore stimulating hormone ( -MSH) for the winter flounder Pleuronectes americanus when mixtures of the two were tested on melanophore preparations. Melanophores from individual pattern components displayed different relative sensitivities to the two hormones. These differences indicate that there are pattern-related variations in MCH and -MSH receptor density and affinity suggesting that these hormones may have modulatory roles on the pattern-related differential neural regulation of the melanophores. 2000 The Fisheries Society of the British Isles

Salmonid gene expression biomarkers indicative of physiological responses to changes in salinity, temperature, but not dissolved oxygen

“…This result may be associated with the effects of skin pigmentation controlling hormones, including α-melanophore stimulating hormone (αMSH) and melanin concentrating hormone (MCH). These hormones are pleiotropic by not only controlling skin pigmentation, but also regulating the response to other stressors (Burton and Vokey, 2000).…”

Salmonid gene expression biomarkers indicative of physiological responses to changes in salinity, temperature, but not dissolved oxygen

“…This result may be associated with the effects of skin pigmentation controlling hormones, including α-melanophore stimulating hormone (αMSH) and melanin concentrating hormone (MCH). These hormones are pleiotropic by not only controlling skin pigmentation, but also regulating the response to other stressors (Burton and Vokey, 2000).…”

Flatfish (Pleuronectiformes) chromatic biology

“…However, varying the balance between antagonistic MSH and MCH in vitro can influence the degree of melanosome dispersion and aggregation (Burton and Vokey 2000a). Thus, flatfish melanophores appear to possess receptors for both of these hormones and their role in these fish may be to facilitate the maintenance of chromatic equilibrium states over prolonged periods.…”

Epigenetic Plasticity of Fish Pigmentation Under Environmental Stress: A Gene–Environment–Epigenetic Interaction Model

“…Dark‐tank environments increase tyr and mitf expression through promoter hypomethylation, resulting in enhanced melanogenesis, whereas white or light backgrounds induce hypermethylation and paler phenotypes [155]. Similar responses across trout, turbot, flounder, and tilapia indicate a conserved visual–neuroendocrine–epigenetic axis [51, 57, 219, 220].…”

Salmonid gene expression biomarkers indicative of physiological responses to changes in salinity, temperature, but not dissolved oxygen

“…This result may be associated with the effects of skin pigmentation controlling hormones, including α-melanophore stimulating hormone (αMSH) and melanin concentrating hormone (MCH). These hormones are pleiotropic by not only controlling skin pigmentation, but also regulating the response to other stressors (Burton and Vokey, 2000).…”

Flatfish (Pleuronectiformes) chromatic biology

“…However, varying the balance between antagonistic MSH and MCH in vitro can influence the degree of melanosome dispersion and aggregation (Burton and Vokey 2000a). Thus, flatfish melanophores appear to possess receptors for both of these hormones and their role in these fish may be to facilitate the maintenance of chromatic equilibrium states over prolonged periods.…”

Epigenetic Plasticity of Fish Pigmentation Under Environmental Stress: A Gene–Environment–Epigenetic Interaction Model

“…Dark‐tank environments increase tyr and mitf expression through promoter hypomethylation, resulting in enhanced melanogenesis, whereas white or light backgrounds induce hypermethylation and paler phenotypes [155]. Similar responses across trout, turbot, flounder, and tilapia indicate a conserved visual–neuroendocrine–epigenetic axis [51, 57, 219, 220].…”

Salmonid gene expression biomarkers indicative of physiological responses to changes in salinity, temperature, but not dissolved oxygen

“…This result may be associated with the effects of skin pigmentation controlling hormones, including α-melanophore stimulating hormone (αMSH) and melanin concentrating hormone (MCH). These hormones are pleiotropic by not only controlling skin pigmentation, but also regulating the response to other stressors (Burton and Vokey, 2000).…”

Flatfish (Pleuronectiformes) chromatic biology

“…However, varying the balance between antagonistic MSH and MCH in vitro can influence the degree of melanosome dispersion and aggregation (Burton and Vokey 2000a). Thus, flatfish melanophores appear to possess receptors for both of these hormones and their role in these fish may be to facilitate the maintenance of chromatic equilibrium states over prolonged periods.…”

Epigenetic Plasticity of Fish Pigmentation Under Environmental Stress: A Gene–Environment–Epigenetic Interaction Model

“…Dark‐tank environments increase tyr and mitf expression through promoter hypomethylation, resulting in enhanced melanogenesis, whereas white or light backgrounds induce hypermethylation and paler phenotypes [155]. Similar responses across trout, turbot, flounder, and tilapia indicate a conserved visual–neuroendocrine–epigenetic axis [51, 57, 219, 220].…”