The Relationship of Atopic Allergy and Dermatitis

Specific hyposensitization in atopic dermatitis

“…(5) All the patients with the first four essential criteria had a similar clinical picture. None had only the more usual prurigo-like picture with hchenification, or patches of true discoid eczema, although there are clinical and experimental precedents for beUeving that any type of eczema can be aggravated by IgE-mediated reactions (Jillson & Adami, 1955;Strauss & Kligman, 1957). All our patients did show the typical prurigo and lichenification but also showed rather diffuse ill-defined erythema, at times merging into atopic erythroderma-the sort of picture which might suggest an immediate weal type sensitivity.…”

“…Hyposensitization is rarely used in the management of atopic dermatitis, though it has been attempted in occasional cases over many years (Strauss & Kligman, 1957;Rajka, 1975), and in a small controlled trial (Kaufman & Roth, 1974). It has even been considered that atopic dermatitis is a contraindication to hyposensitization treatment for other allergies.…”

Sensitivity to House‐dust Mites in Atopic Dermatitis

“…Strauss & Kligmann (9) conjectured that an ingested or inhaled protein allergen would tend to accumulate in inflamed skin areas and could thus give rise to itching and exacerbation of the eczema. Strauss & Kligmann (9) conjectured that an ingested or inhaled protein allergen would tend to accumulate in inflamed skin areas and could thus give rise to itching and exacerbation of the eczema.…”

Value of Patch Tests in Dermatology

“…It is not known whether the tan polish contains chrome, to which our patient (Case 1) was allergie. Dentón et al 18 found sufficient chromate in cements in the United States to produce allergic reactions in hypersensi¬ tive patients, such as our Case 2.…”