The relationship between the development of erythroderma in patients with atopic dermatitis and the avoidance of anti-inflammatory topical drugs

Burden of illness, medication adherence, and unmet medical needs in Japanese patients with atopic dermatitis: A retrospective analysis of a cross‐sectional questionnaire survey

“…15 Ueno et al 15 developed the medication adherence scale for Japanese patients with chronic disease, including AD. The total scale ranges 14-70 (excellent) and includes four factors: medication compliance (range, [3][4][5][6][7][8][9][10][11][12][13][14][15]; collaboration with health-care providers (range, [3][4][5][6][7][8][9][10][11][12][13][14][15]; willingness to access and use information about medication (range, ; and acceptance to take medication and how taking medication fits the patient's lifestyle (range, [3][4][5][6][7][8][9][10][11][12][13][14][15].…”

“…2,3 Topical corticosteroids (TCS) and tacrolimus ointment are the main anti-inflammatory treatments used for AD. 1,4,5 Patients' interruption and inadequate use of these topical anti-inflammatory drugs can lead to aggravation of AD, 6 and non-adherence to therapy is problematic and has been associated with poor therapeutic outcomes. 7 To improve adherence, health-care providers are expected to explain the importance of medications to patients and motivate them to adhere to treatment.…”

Longitudinal prevalence of atopic dermatitis among freshmen at Hiroshima University between 2002 and 2019

“…In Japan, both the prevalence of AD in students around the age of 19 and the proportion of patients with moderate to severe AD have increased slightly since 2000. AD may have a better prognosis in the future with appropriate treatment 10 . The results in this study highlight the need for action to be taken with school‐aged children before they reach adulthood to reverse the increase in the prevalence of AD in adults.…”

“…The reported eczema prevalence in adults is 7.2% in the USA, 7 and the prevalence of adult AD ranges from 2.2% to 17.6% in European Union countries. 8 A Japanese study of young staff members in their 20s reported AD prevalence rates of 10 The results in this study highlight the need for action to be taken with school-aged children before they reach adulthood to reverse the increase in the prevalence of AD in adults.…”