The Relationship Between Proximal Femoral Anatomy and Osteoarthrosis of the Hip

Hj, Mills; Jg, Horne; Gl, Purdie

doi:10.1097/00003086-199303000-00026

Cited by 22 publications

(18 citation statements)

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“…al used radiographic images to measure certain geometric features and their relationship to OA [43] and did not observe a relationship between hip OA and the neck shaft angle. Another study measured geometric parameters on radiographs and observed that a higher NSA was related to incidence of OA [44]. While our results may suggest coxa valga as a possible early manifestation of OA or even a geometrical risk factor, a study conducted by Doherty et al [21] performed on radiographs exhibited the opposite results as the current study.…”

Section: Discussioncontrasting

confidence: 93%

Study of the interactions between proximal femur 3d bone shape, cartilage health, and biomechanics in patients with hip Osteoarthritis

Pedoia

Samaan

Inamdar

et al. 2017

Journal Orthopaedic Research

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In this study quantitative MRI and gait analysis were used to investigate the relationships between proximal femur 3D bone shape, cartilage morphology, cartilage biochemical composition, and joint biomechanics in subject with hip Osteoarthritis (OA). Eighty subjects underwent unilateral hip MR-imaging: T1ρ and T2 relaxation times were extracted through voxel based relaxometry and bone shape was assessed with 3D MRI-based statistical shape modeling. In addition, 3D gait analysis was performed in seventy-six of the studied subjects. Associations between shape, cartilage lesion presence, severity, and cartilage T1ρ and T2 were analyzed with linear regression and statistical parametric mapping. An ad hoc analysis was performed to investigate biomechanics and shape associations. Our results showed that subjects with a higher neck shaft angle in the coronal plane (higher mode 1, coxa valga), thicker femoral neck and a less spherical femoral head (higher mode 5, pistol grip) exhibited more severe acetabular and femoral cartilage abnormalities, showing different interactions with demographics factors. Subjects with coxa valga also demonstrated a prolongation of T1ρ and T2. Subjects with pistol grip deformity exhibited reduced hip internal rotation angles and subjects with coxa valga exhibited higher peak hip adduction moment and moment impulse. The results of this study establish a clear relationship between 3D proximal femur shape variations and markers of hip joint degeneration-morphological, compositional, well as insight on the possible interactions with demographics and biomechanics, suggesting that 3D MRI-based bone shape maybe a promising biomarker of early hip joint degeneration. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:330-341, 2018.

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Section: Discussioncontrasting

confidence: 93%

Study of the interactions between proximal femur 3d bone shape, cartilage health, and biomechanics in patients with hip Osteoarthritis

Pedoia

Samaan

Inamdar

et al. 2017

Journal Orthopaedic Research

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“…There is no consensus regarding the association of neck-shaft angle and the development of hip osteoarthritis, with study reports ranging from no association [47,49] to a positive correlation between a larger angle [50], a smaller angle [51], or both [45] with osteoarthritis. During the progression of hip osteoarthritis, the femoral head flattens and the femoral neck shortens [52].…”

Section: Alterations In Femoral Neck-shaft Anglementioning

confidence: 99%

Relationship between joint shape and the development of osteoarthritis

Baker-LePain

Lane²

2010

Current Opinion in Rheumatology

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Purpose of review To present an updated summary of the relationship between joint shape and the development of osteoarthritis, with a particular focus on osteoarthritis of the hip. Recent findings Osteoarthritis of the hip is highly heritable, with a genetic contribution estimated at 60%. Among the genes that have been linked to this disease are several that are involved in the development and maintenance of joint shape, including members of the Wingless (Wnt) and the bone morphogenetic protein (BMP) family. Several features of hip joint architecture, such as acetabular dysplasia, pistol grip deformity, wide femoral neck, altered femoral neck-shaft angle, appear to play an important role in the pathogenesis of osteoarthritis and may predate the development of osteoarthritis by decades. Summary Gene–environment interactions play a crucial role in the development of osteoarthritis. The architecture of joint shape is determined by a complex sequence spanning embryonic, childhood, and adult life and contributes to the pathogenesis of osteoarthritis.

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“…Control groups for fracture‐risk studies often contain a disproportionate number of osteoarthritic hips. Joint space narrowing, stiffness, and other anatomic features of osteoarthritis may affect apparent hip shape, (21) thus this diagnosis should be identified and considered in any morphometric study.…”

Section: Introductionmentioning

confidence: 99%

Femoral Neck Length and Hip Fracture Risk

Michelotti

Clark

1999

Journal of Bone and Mineral Research

100

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To determine whether there are differences in femoral skeletal geometry in fracture-prone subjects when size, positioning diagnosis, and age are controlled, we compared femoral measurements made from the uninvolved hip on 119 plane anteroposterior pelvis radiographs of women without fracture to those of the contralateral hip in a group of 43 female patients with hip fractures (neck, 23; intertrochanteric, 20). The hip was imaged in a standardized position of rotation and adduction. Race, age, and musculoskeletal diagnosis were known. Subjects were grouped by diagnosis of the opposite hip condition (rheumatoid arthritis, osteoarthritis, and normal) and compared. Measurements were also analyzed as ratios to head diameter (HD), neck diameter (ND), and pelvic width. Femoral neck length (NL) was measured from skeletal preparations and imaged in controlled positions of abduction and external rotation. No differences were found between the neck and intertrochanteric fracture groups. The differences between the fracture group and the controls were a thinner femoral cortex (measured at a point one head radius below the lesser trochanter) a larger femoral head, and a larger femoral ND in the fracture group (p < 0.025). The difference in cortical thickness was still significant when scaled by size, but the ratio of HD to ND was equivalent in fractures and controls. No difference in femoral NL could be demonstrated. The experimental measurements showed that apparent NL is significantly position sensitive and this may explain previously reported differences in fracture

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The Relationship Between Proximal Femoral Anatomy and Osteoarthrosis of the Hip

Cited by 22 publications

References 0 publications

Study of the interactions between proximal femur 3d bone shape, cartilage health, and biomechanics in patients with hip Osteoarthritis

Study of the interactions between proximal femur 3d bone shape, cartilage health, and biomechanics in patients with hip Osteoarthritis

Relationship between joint shape and the development of osteoarthritis

Femoral Neck Length and Hip Fracture Risk

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