“…Immediate hypersensitivity to indoor allergens is strongly associated with bronchial asthma [1,2]. In Singapore, one in five school children have been identified with doctor-diagnosed asthma [3].…”
These results provide evidence that Bt allergens are distinct and have relatively low to moderate cross-reactivity with Dermatophagoides spp. allergens. Bt allergens should therefore be included in the diagnostic panel for the evaluation of allergic disorders in the tropics, and the development of new diagnostic and therapeutic strategies should include allergens of Bt.
“…Immediate hypersensitivity to indoor allergens is strongly associated with bronchial asthma [1,2]. In Singapore, one in five school children have been identified with doctor-diagnosed asthma [3].…”
These results provide evidence that Bt allergens are distinct and have relatively low to moderate cross-reactivity with Dermatophagoides spp. allergens. Bt allergens should therefore be included in the diagnostic panel for the evaluation of allergic disorders in the tropics, and the development of new diagnostic and therapeutic strategies should include allergens of Bt.
“…Immediate hypersensitivity to indoor allergens is associated with bronchial asthma in children and young adults |l|. These allergens not only trigger acute attacks of asthma, but chronic exposure is also an important cause of airway inflammation [2][3][4]. In Singapore, one in five schoolchildren have been identified with doctor-diagnosed asthma [5|.…”
The results indicate that compared with public places, the home consitutes a major reservior of indoor allergens. Allergens of the storage mite, B. tropicalis, should be considered as a major allergenic component of dust in Singapore.
“…House‐dust mites have been shown to play an important role in the pathogenesis of asthma and atopic diseases ( 1, 2). Mites are found almost all over the world, but their fauna differs between regions ( 3).…”
Asthma and/or allergic rhinitis patients were highly sensitized to the local dust-mite fauna. Thus, these dust mites should be considered important allergenic sources of this region.
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