The relation of the weight of the heart to the weight of the body and of the weight of the heart to age

Smith, Harry L.

doi:10.1016/s0002-8703(29)90099-5

Cited by 178 publications

(52 citation statements)

References 2 publications

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“…It was continued during the collection of the blood samples, until collection of expired air and sampling of right atrial blood had been completed. The total duration of exercise was slightly less than 10 The coronary blood flow was calculated according to the method previously described.la, b Gregg has shown that the coronary sinus drains primarily left ventricular muscle. Consequently, the nitrous oxide method measures primarily the flow through a unit (100 Gm.)…”

Section: Methodsmentioning

confidence: 99%

The Effect of Exercise on Coronary Blood Flow, Myocardial Oxygen Consumption and Cardiac Efficiency in Man

et al. 1953

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It has been known that exercise causes an increase in the coronary blood flow in animals. The present work has been carried out to study the effect of exercise on coronary blood flow and myocardial oxygen consumption of the human heart in vivo. The results indicate that the heart responds to the increased load of exercise with a rise in coronary blood flow. Since the arteriovenous coronary oxygen difference shows little change, the increase in oxygen consumption of the heart muscle is primarily the result of an increased coronary blood flow. As the cardiac work rises more than the myocardial oxygen consumption, the left ventricular efficiency increases. The response of the failing heart muscle to acute increases in load produced by exercise does not differ from that of the normal heart or of the isolated heart. C ATHETERIZATION of the coronary sinus in man in conjunction with the nitrous oxide method has made it possible to determine coronary blood flow and myocardial oxygen consumption in man.1'2 Until now, the method has been used to follow the behavior of human heart muscle of resting individuals only.3 A study of the coronary circulation and myocardial oxygen consumption during exercise would appear to be of interest, because exercise constitutes a temporary increase in load to which the heart must adjust itself by coronary circulatory and metabolic changes. The alterations in the coronary circulation and myocardial oxygen consumption are of particular importance since it is during in-

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Section: Methodsmentioning

confidence: 99%

The Effect of Exercise on Coronary Blood Flow, Myocardial Oxygen Consumption and Cardiac Efficiency in Man

et al. 1953

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“…Furthermore, when other tables are used [19] the same cases are classified as cardiomegaly as in this study. Although measuring heart weight at autopsy is considered a good method of assessing cardiomegaly, the autopsies performed in this study are part of routine service and weights may not have all been measured with the care of a scientific study.…”

Section: Discussionmentioning

confidence: 99%

Cardiothoracic ratio (CTR) measured on post-mortem computed tomography (PMCT) – Pre- and post-ventilation

James

Morgan

Rutty

et al. 2016

Journal of Forensic Radiology and Imaging

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“…diastolic, yet 25 hearts were enlarged more than 20 per cent beyond the limits defined as normal by Smith. 25 Willius and Smith,20 however, have shown that myocardial injury by infection or its toxins in some instances permits the heart to respond by hypertrophy.…”

Section: Commentmentioning

confidence: 99%

Cardiac lesions in rheumatoid arthritis

Goehrs

Baggenstoss

Slocumb

1960

Arthritis & Rheumatism

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The relation of the weight of the heart to the weight of the body and of the weight of the heart to age

Cited by 178 publications

References 2 publications

The Effect of Exercise on Coronary Blood Flow, Myocardial Oxygen Consumption and Cardiac Efficiency in Man

The Effect of Exercise on Coronary Blood Flow, Myocardial Oxygen Consumption and Cardiac Efficiency in Man

Cardiothoracic ratio (CTR) measured on post-mortem computed tomography (PMCT) – Pre- and post-ventilation

Cardiac lesions in rheumatoid arthritis

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