The Relation of Spike Foci and of Clinical Seizure Characteristics to Different Patterns of Mesial Temporal Atrophy

Longitudinal analysis of interictal electroencephalograms in patients with temporal lobe epilepsy with hippocampal sclerosis

“…Our findings are in agreement with previous studies that demonstrated that IEDs are confined to the temporal lobe in patients with HS [10,28], and that IEDs found to be confined to one temporal lobe on serial routine EEGs or during long-term video EEG monitoring may be sufficient to localize the epileptogenic zone in patients with TLE and unilateral HS [29,30]. Also, there is evidence that concordant IEDs and MRI in pharmacoresistant TLE-HS patients is associated with good surgical outcomes [10,31,32]. A recent prospective study from our group showed that predominantly ipsilateral IEDs on serial outpatient EEGs in patients with unilateral TLE-HS and no suspicion of nonepileptic events can obviate the need for video EEG monitoring, based on our finding of similar surgical outcomes in these patients as those who underwent video-EEG for seizure recording [30].…”

“…Our findings are in agreement with previous studies that demonstrated that IEDs are confined to the temporal lobe in patients with HS [10,28], and that IEDs found to be confined to one temporal lobe on serial routine EEGs or during long-term video EEG monitoring may be sufficient to localize the epileptogenic zone in patients with TLE and unilateral HS [29,30]. Also, there is evidence that concordant IEDs and MRI in pharmacoresistant TLE-HS patients is associated with good surgical outcomes [10,31,32].…”

Longitudinal analysis of interictal electroencephalograms in patients with temporal lobe epilepsy with hippocampal sclerosis

“…Our findings are in agreement with previous studies that demonstrated that IEDs are confined to the temporal lobe in patients with HS [10,28], and that IEDs found to be confined to one temporal lobe on serial routine EEGs or during long-term video EEG monitoring may be sufficient to localize the epileptogenic zone in patients with TLE and unilateral HS [29,30]. Also, there is evidence that concordant IEDs and MRI in pharmacoresistant TLE-HS patients is associated with good surgical outcomes [10,31,32]. A recent prospective study from our group showed that predominantly ipsilateral IEDs on serial outpatient EEGs in patients with unilateral TLE-HS and no suspicion of nonepileptic events can obviate the need for video EEG monitoring, based on our finding of similar surgical outcomes in these patients as those who underwent video-EEG for seizure recording [30].…”

“…Our findings are in agreement with previous studies that demonstrated that IEDs are confined to the temporal lobe in patients with HS [10,28], and that IEDs found to be confined to one temporal lobe on serial routine EEGs or during long-term video EEG monitoring may be sufficient to localize the epileptogenic zone in patients with TLE and unilateral HS [29,30]. Also, there is evidence that concordant IEDs and MRI in pharmacoresistant TLE-HS patients is associated with good surgical outcomes [10,31,32].…”

Mild Non-lesional Temporal Lobe Epilepsy: A Common, Unrecognized Disorder with Onset in Adulthood

“…In contrast, more diffuse temporal lobe damage correlates with larger interictal EEG foci and more frequent secondary generalized seizures. 23 The clinical features, seizure patterns, interictal EEG, and benign nature of the mild non-lesional TLE are very similar to those of familial TLE. 10 ' 24 It is noteworthy that such a diagnosis could be ascertained or suspected in nine of the patients presented here.…”

Is inpatient ictal video‐electroencephalographic monitoring mandatory in mesial temporal lobe epilepsy with unilateral hippocampal sclerosis? A prospective study

“…4,6 However, the real need for this examination in MTLE patients with clear MRI signs of unilateral HS has already been questioned. 4,6,10,11 Concordant MRI and well-lateralized interictal EEG were also correlated with good surgical outcome, which means that the combination of these methods could correctly identify the epileptogenic zone. 4,6,10,11 Concordant MRI and well-lateralized interictal EEG were also correlated with good surgical outcome, which means that the combination of these methods could correctly identify the epileptogenic zone.…”

“…5 Strong concordance between interictal and ictal EEG findings with unilateral HS in the preoperative evaluation of patients with temporal lobe epilepsy (TLE) has been demonstrated. 4,6,10,11 Concordant MRI and well-lateralized interictal EEG were also correlated with good surgical outcome, which means that the combination of these methods could correctly identify the epileptogenic zone. 12 There are a couple of studies evaluating surgical outcome of TLE patients who received surgery without VEEG, 13,14 but none of them has investigated a homogeneous cohort of TLE patients with long-term postoperative evaluation comparing those with and without VEEG recordings.…”

Longitudinal analysis of interictal electroencephalograms in patients with temporal lobe epilepsy with hippocampal sclerosis

“…Our findings are in agreement with previous studies that demonstrated that IEDs are confined to the temporal lobe in patients with HS [10,28], and that IEDs found to be confined to one temporal lobe on serial routine EEGs or during long-term video EEG monitoring may be sufficient to localize the epileptogenic zone in patients with TLE and unilateral HS [29,30]. Also, there is evidence that concordant IEDs and MRI in pharmacoresistant TLE-HS patients is associated with good surgical outcomes [10,31,32]. A recent prospective study from our group showed that predominantly ipsilateral IEDs on serial outpatient EEGs in patients with unilateral TLE-HS and no suspicion of nonepileptic events can obviate the need for video EEG monitoring, based on our finding of similar surgical outcomes in these patients as those who underwent video-EEG for seizure recording [30].…”

“…Our findings are in agreement with previous studies that demonstrated that IEDs are confined to the temporal lobe in patients with HS [10,28], and that IEDs found to be confined to one temporal lobe on serial routine EEGs or during long-term video EEG monitoring may be sufficient to localize the epileptogenic zone in patients with TLE and unilateral HS [29,30]. Also, there is evidence that concordant IEDs and MRI in pharmacoresistant TLE-HS patients is associated with good surgical outcomes [10,31,32].…”

Mild Non-lesional Temporal Lobe Epilepsy: A Common, Unrecognized Disorder with Onset in Adulthood

“…In contrast, more diffuse temporal lobe damage correlates with larger interictal EEG foci and more frequent secondary generalized seizures. 23 The clinical features, seizure patterns, interictal EEG, and benign nature of the mild non-lesional TLE are very similar to those of familial TLE. 10 ' 24 It is noteworthy that such a diagnosis could be ascertained or suspected in nine of the patients presented here.…”

Is inpatient ictal video‐electroencephalographic monitoring mandatory in mesial temporal lobe epilepsy with unilateral hippocampal sclerosis? A prospective study

“…4,6 However, the real need for this examination in MTLE patients with clear MRI signs of unilateral HS has already been questioned. 4,6,10,11 Concordant MRI and well-lateralized interictal EEG were also correlated with good surgical outcome, which means that the combination of these methods could correctly identify the epileptogenic zone. 4,6,10,11 Concordant MRI and well-lateralized interictal EEG were also correlated with good surgical outcome, which means that the combination of these methods could correctly identify the epileptogenic zone.…”

“…5 Strong concordance between interictal and ictal EEG findings with unilateral HS in the preoperative evaluation of patients with temporal lobe epilepsy (TLE) has been demonstrated. 4,6,10,11 Concordant MRI and well-lateralized interictal EEG were also correlated with good surgical outcome, which means that the combination of these methods could correctly identify the epileptogenic zone. 12 There are a couple of studies evaluating surgical outcome of TLE patients who received surgery without VEEG, 13,14 but none of them has investigated a homogeneous cohort of TLE patients with long-term postoperative evaluation comparing those with and without VEEG recordings.…”

Longitudinal analysis of interictal electroencephalograms in patients with temporal lobe epilepsy with hippocampal sclerosis

“…Our findings are in agreement with previous studies that demonstrated that IEDs are confined to the temporal lobe in patients with HS [10,28], and that IEDs found to be confined to one temporal lobe on serial routine EEGs or during long-term video EEG monitoring may be sufficient to localize the epileptogenic zone in patients with TLE and unilateral HS [29,30]. Also, there is evidence that concordant IEDs and MRI in pharmacoresistant TLE-HS patients is associated with good surgical outcomes [10,31,32]. A recent prospective study from our group showed that predominantly ipsilateral IEDs on serial outpatient EEGs in patients with unilateral TLE-HS and no suspicion of nonepileptic events can obviate the need for video EEG monitoring, based on our finding of similar surgical outcomes in these patients as those who underwent video-EEG for seizure recording [30].…”

“…Our findings are in agreement with previous studies that demonstrated that IEDs are confined to the temporal lobe in patients with HS [10,28], and that IEDs found to be confined to one temporal lobe on serial routine EEGs or during long-term video EEG monitoring may be sufficient to localize the epileptogenic zone in patients with TLE and unilateral HS [29,30]. Also, there is evidence that concordant IEDs and MRI in pharmacoresistant TLE-HS patients is associated with good surgical outcomes [10,31,32].…”

Mild Non-lesional Temporal Lobe Epilepsy: A Common, Unrecognized Disorder with Onset in Adulthood

“…In contrast, more diffuse temporal lobe damage correlates with larger interictal EEG foci and more frequent secondary generalized seizures. 23 The clinical features, seizure patterns, interictal EEG, and benign nature of the mild non-lesional TLE are very similar to those of familial TLE. 10 ' 24 It is noteworthy that such a diagnosis could be ascertained or suspected in nine of the patients presented here.…”

Is inpatient ictal video‐electroencephalographic monitoring mandatory in mesial temporal lobe epilepsy with unilateral hippocampal sclerosis? A prospective study

“…4,6 However, the real need for this examination in MTLE patients with clear MRI signs of unilateral HS has already been questioned. 4,6,10,11 Concordant MRI and well-lateralized interictal EEG were also correlated with good surgical outcome, which means that the combination of these methods could correctly identify the epileptogenic zone. 4,6,10,11 Concordant MRI and well-lateralized interictal EEG were also correlated with good surgical outcome, which means that the combination of these methods could correctly identify the epileptogenic zone.…”

“…5 Strong concordance between interictal and ictal EEG findings with unilateral HS in the preoperative evaluation of patients with temporal lobe epilepsy (TLE) has been demonstrated. 4,6,10,11 Concordant MRI and well-lateralized interictal EEG were also correlated with good surgical outcome, which means that the combination of these methods could correctly identify the epileptogenic zone. 12 There are a couple of studies evaluating surgical outcome of TLE patients who received surgery without VEEG, 13,14 but none of them has investigated a homogeneous cohort of TLE patients with long-term postoperative evaluation comparing those with and without VEEG recordings.…”