The relation between diarrhoeal episodes in infancy and both blood pressure and sodium intake in later life: The Newcastle Thousand Families Study

Pearce, Mark S.; Relton, Caroline L; Unwin, Nigel; Adamson, Ashley J.; Smith, George Davey

doi:10.1038/jhh.2008.45

Cited by 6 publications

(10 citation statements)

References 10 publications

(12 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our study is in line with two UK cohorts 3 4. An historical cohort based on over 5000 men and women born in 1920–1939 in Hertfordshire found no relationship of health visitor-recorded episodes of diarrhoea recalled by the mother in infancy and childhood with blood pressure or coronary heart disease after age 64 years 3.…”

Section: Discussionsupporting

confidence: 90%

“…However, sodium intake in adulthood was associated with infancy diarrhoea, providing partial support for the original hypothesis 1 5. The prevalence of infant diarrhoea was modest in Hertfordshire (n=171)3 and Newcastle (27 of 408 children),4 and the coefficients in the current study are estimated more precisely.…”

Section: Discussionsupporting

confidence: 66%

“…An historical cohort based on over 5000 men and women born in 1920–1939 in Hertfordshire found no relationship of health visitor-recorded episodes of diarrhoea recalled by the mother in infancy and childhood with blood pressure or coronary heart disease after age 64 years 3. The Newcastle Thousand Families Study also observed no association of health visitor-recorded diarrhoea in infants born in 1947 with systolic or diastolic blood pressure or carotid artery intima-media thickness at age 50 years 4. However, sodium intake in adulthood was associated with infancy diarrhoea, providing partial support for the original hypothesis 1 5.…”

Section: Discussionmentioning

confidence: 98%

“…Hospitalisation for dehydration in early infancy was positively associated with blood pressure 1. Others found no relationship between diarrhoea and cardiovascular disease risk 3 4…”

mentioning

confidence: 99%

See 3 more Smart Citations

Do gastrointestinal tract infections in infancy increase blood pressure in childhood? A cohort study

Martin

Kramer²,

Dahhou³

et al. 2009

Journal of Epidemiology & Community Health

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 66%

Section: Discussionmentioning

confidence: 98%

“…Hospitalisation for dehydration in early infancy was positively associated with blood pressure 1. Others found no relationship between diarrhoea and cardiovascular disease risk 3 4…”

mentioning

confidence: 99%

See 2 more Smart Citations

Do gastrointestinal tract infections in infancy increase blood pressure in childhood? A cohort study

Martin

Kramer²,

Dahhou³

et al. 2009

Journal of Epidemiology & Community Health

View full text Add to dashboard Cite

show abstract

“…A small number of studies have suggested that dehydration in infancy is associated with higher adult blood pressure, possibly because of dehydration and later salt retention 3 4. Higher reported salt intake has been found among adults who experienced diarrhoea in infancy 5. Some studies have reported a lack of association between infancy diarrhoea and blood pressure, coronary heart diseases or intima media thickness in adults 6–8…”

mentioning

confidence: 99%

Association of diarrhoea, poor hygiene and poor social conditions in childhood with blood pressure in adulthood

Kauhanen

Lynch

Lakka

et al. 2009

Journal of Epidemiology & Community Health

View full text Add to dashboard Cite

show abstract

Associations Between Household and Neighbourhood Socioeconomic Status and Systolic Blood Pressure Among Urban South African Adolescents

et al. 2012

View full text Add to dashboard Cite

SummaryFactors resulting in high risk for cardiovascular disease have been well studied in high income countries, but have been less well researched in low/middle income countries. This is despite robust theoretical evidence of environmental transitions in such countries which could result in biological adaptations that lead to increased hypertension and cardiovascular disease risk. Data from the South African Birth to Twenty cohort, Bone Health sub-sample (n=358, 47% female), were used to model associations between household socioeconomic status (SES) in infancy, household/neighbourhood SES at age 16 years, and systolic blood pressure (multivariate linear regression) and risk for systolic pre-hypertension (binary logistic regression). Bivariate analyses revealed household/neighbourhood SES measures that were significantly associated with increased systolic blood pressure. These significant associations included improved household sanitation in infancy/16 years, caregiver owning the house in infancy and being in a higher tertile (higher SES) of indices measuring school problems/environment or neighbourhood services/problems/crime at 16 years of age. Multivariate analyses adjusted for sex, maternal age, birth weight, parity, smoking, term birth, height/body mass index at 16 years. In adjusted analyses, only one SES variable remained significant for females: those in the middle tertile of the crime prevention index had higher systolic blood pressure (β=3.52, SE=1.61) compared with the highest tertile (i.e. those with the highest crime prevention). In adjusted analyses, no SES variables were significantly associated with the systolic blood pressure of boys, or with the risk of systolic pre-hypertension in either sex. The lack of association between SES and systolic blood pressure/systolic pre-hypertension at age 16 years is consistent with other studies showing an equalization of adolescent health inequalities. Further testing of the association between SES and systolic blood pressure would be recommended in adulthood to see whether the lack of association persists.

show abstract

The relation between diarrhoeal episodes in infancy and both blood pressure and sodium intake in later life: The Newcastle Thousand Families Study

Cited by 6 publications

References 10 publications

Do gastrointestinal tract infections in infancy increase blood pressure in childhood? A cohort study

Do gastrointestinal tract infections in infancy increase blood pressure in childhood? A cohort study

Association of diarrhoea, poor hygiene and poor social conditions in childhood with blood pressure in adulthood

Associations Between Household and Neighbourhood Socioeconomic Status and Systolic Blood Pressure Among Urban South African Adolescents

Contact Info

Product

Resources

About