volume 131, issue 1, P81-92 2004
DOI: 10.1016/j.chemphyslip.2004.04.004
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Abstract: Phosphatidylcholines (PCs) having an acyl chain with a 2,4-dienal terminal are expected to be important bioactive compounds formed during lipid peroxidation in vivo. However, they have not been isolated from biological tissues. Here we used electrospray mass spectroscopy to investigate whether a high autoxidative instability may contribute to the difficulty in detecting one such compound, 13-oxo-9,11-tridecadienoyl PC (OTDA-PC, 1). Although we found that pure, synthetic OTDA-PC was very stable, OTDA-PC formed …

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