2018
DOI: 10.22159/ajpcr.2018.v11i10.24993
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Abstract: Objectives: Exposure to α-cypermethrin (α-CP) may yield reactive oxygen species (ROS) that is responsible for oxidative stress in mammals. A variety of antioxidants were used to alleviate α-CP-induced toxicity in experimental animals. To the best of our knowledge, there are no attempts of using Moringa oleifera L. (MO) plant extracts against α-CP-induced toxicity. Therefore, this study was conducted.Methods: A total of 16 adult female rats were segregated into equally four groups: One group administered α-CP o… Show more

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Cited by 5 publications
(4 citation statements)
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References 42 publications
(45 reference statements)
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“…In the present investigation decreased mortality may be due to boosting up scavenging activity of free radicals by Moringa oleifera. Administration of MLE restored the activities of AST, ALT, ALP, LDH, GGT and total protein toward the normal level induced by pesticides as shown by many workers [26,51,52]. The reversal of increased transaminases by MLE supplement may be due to the healing of hepatic parenchyma and regeneration of hepatocytes.…”
Section: Discussionmentioning
confidence: 64%
See 1 more Smart Citation
“…In the present investigation decreased mortality may be due to boosting up scavenging activity of free radicals by Moringa oleifera. Administration of MLE restored the activities of AST, ALT, ALP, LDH, GGT and total protein toward the normal level induced by pesticides as shown by many workers [26,51,52]. The reversal of increased transaminases by MLE supplement may be due to the healing of hepatic parenchyma and regeneration of hepatocytes.…”
Section: Discussionmentioning
confidence: 64%
“…Khalil and Korni (2017) have also been reported that Moringa oleifera leaves extract helps in boosting growth, immune system by mitigate oxidative stress in fishes [24]. Previous studies reported the attenuating effect of Moringa leaf extract against pesticides in rats and fishes [25,26].…”
Section: Introductionmentioning
confidence: 99%
“…Dalam kondisi seperti ini, beban kerja tubuh menjadi semakin berat yang membuat sistem imun tubuh menurun dan menyebabkan peradangan. Saat terjadi peradangan tubuh akan melawan dengan mengeluarkan zat anti peradangan melalui reaksi oksidasi yang berguna namun menimbulkan dampak buruk yang berbahaya dibanding peradangan itu sendiri (Wang et al, 2017, Mansour et al, 2018.…”
Section: Pembahasanunclassified
“…Pesticides could include herbicides, insecticides, fungicides, disinfectant, and rodenticides [1]. Among the various pesticides, insecticides are the most widely used with cypermethrin (CY) and chlorpyrifos (CH) been the dominant chemicals applied [3,4]. CY is a synthetic, pyrethroid insecticide used to control many pests on crops.…”
Section: Introductionmentioning
confidence: 99%