2018
DOI: 10.1371/journal.pone.0195302 View full text |Buy / Rent full text
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Abstract: Foot-and-mouth disease (FMD) is an acute, highly contagious viral disease of domestic and wild cloven-hoofed animals, caused by FMD virus (FMDV). An FMD outbreak can cause major production losses and have significant implications for trade. Vaccination can assist in controlling the disease, and emergency vaccination using high antigen payload vaccines (>6 PD50/dose) is considered an important control approach in the event of an outbreak. In recent years there has been a divergence of serotype A viruses in Sout… Show more

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“…All samples were tested in duplicate and samples with poor Ct value correlation in the duplicate reactions were repeated. Samples with a Ct <40 (equivalent to 1 × 10 3.5 copies RNA/ml blood or 1 × 10 3.2 copies RNA/swab) were considered positive ( 23 ).…”
Section: Methodsmentioning
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“…All samples were tested in duplicate and samples with poor Ct value correlation in the duplicate reactions were repeated. Samples with a Ct <40 (equivalent to 1 × 10 3.5 copies RNA/ml blood or 1 × 10 3.2 copies RNA/swab) were considered positive ( 23 ).…”
Section: Methodsmentioning