2015
DOI: 10.1155/2015/824624
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Abstract: Red blood cell distribution width (RDW) is a measure of red blood cell volume variations (anisocytosis) and is reported as part of a standard complete blood count. In recent years, numerous studies have noted the importance of RDW as a predictor of poor clinical outcomes in the settings of various diseases, including coronary artery disease (CAD). In this paper, we discuss the prognostic value of RDW in CAD and describe the pathophysiological connection between RDW and acute coronary syndrome. In our opinion, … Show more

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Cited by 82 publications
(78 citation statements)
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References 111 publications
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“…Elevated RDW had been shown to predict poor outcomes in the normal population [15,16], in patients with CAD [2][3][4][5][6], and in patients with HF [8][9][10][11][12]. The present analysis is the first to demonstrate the predictive value of RDW both in patients with ischemic and nonischemic LVSD.…”
Section: Discussionmentioning
confidence: 48%
See 1 more Smart Citation
“…Elevated RDW had been shown to predict poor outcomes in the normal population [15,16], in patients with CAD [2][3][4][5][6], and in patients with HF [8][9][10][11][12]. The present analysis is the first to demonstrate the predictive value of RDW both in patients with ischemic and nonischemic LVSD.…”
Section: Discussionmentioning
confidence: 48%
“…In recent years, anisocytosis has emerged as a prognostic biomarker in cardiovascular disease. Numerous studies have noted the relationship between RDW values and adverse clinical outcomes in the setting of coronary artery disease (CAD), including patients undergoing percutaneous coronary interventions in the course of stable coronary artery disease and patients with acute coronary syndromes (ACS) [2][3][4][5][6].…”
Section: Introductionmentioning
confidence: 99%
“…One of the signs of inflammation are red blood cell distribution width (RDW) and neutrophil to lymphocyte ratio (NLR). Red blood cell distribution width (RDW) is a measurement of circulating erythrocyte size variations (Bujak K. et al, 2015). Children with appendicitis either perforated or not, have a significant increase in red blood cells compared to those without appendicitis (p <0.001), but there is no significant difference in red blood cells in children with simple or perforation appendicitis (p = 0.081) (Official Journal of the Japan Pediatric Society Pediatrics International (2016) 58, 202-205).…”
Section: Introductionmentioning
confidence: 99%
“…Cardiac parameters, hemoglobin and red cell maturation were improved and red cell distribution width (RDW) was decreased in PAH patients with CoQ supplementation, consistent with improved mitochondrial synthetic function. Bujak K et al 22 included coronary artery disease (CAD) in the importance of RDW as a predictor of poor clinical outcomes in the settings of various diseases. The negative prognostic effects of elevated RDW levels may be attributed to the adverse effects of independent risk factors such as inflammation, oxidative stress, and vitamin D 3 and iron deficiency on bone marrow function (erythropoiesis).…”
Section: Discussionmentioning
confidence: 99%