The profile of Japanese Association for Acute Medicine – out‐of‐hospital cardiac arrest registry in 2014–2015

Kitamura, Tetsuhisa; Iwami, Taku; Atsumi, Takahiro; Endo, Tomoyuki; Kanna, Tomoo; Kuroda, Yasuhiro; Sakurai, Atsushi; Tasaki, Osamu; Terada, Yoshio; Tsuruta, Ryosuke; Tomio, Jun; Nakata, Kazuyuki; Nachi, Sho; Hase, Mamoru; Hayakawa, Mineji; Hiruma, Takahiro; Hiasa, Kenichi; Muguruma, Takashi; Yano, Takao; Shimazu, Takeshi; Morimura, Naoto

doi:10.1002/ams2.340

Cited by 92 publications

(93 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Elderly patients aged > 65 years accounted for 29.4% of all ECPR cases in the present study, which was similar to ELSO registry data [11], but the percentage was considerably lower than the traditional CPR registry data of 60–70% [10, 32, 34]. This indicates that clinical discretion during CPR consultation favors young patients for ECMO support.…”

Section: Discussionsupporting

confidence: 82%

“…Traditional CPR for patients who experienced OHCA and IHCA was associated with low hospital survival rates, namely 7.2–9.9% [10, 31, 32] and 14.2–15.7% [33, 34], respectively. Notably, most of the patients achieving return of spontaneous circulation (ROSC) were resuscitated for < 30 min (42.5%), whereas only 6% of patients achieving ROSC were resuscitated for > 30 min [33].…”

Section: Discussionmentioning

confidence: 99%

“…Animal experiments have indicated that old and young animals present different degrees of neuroinflammation and apoptosis reaction after brain ischemic damage [5, 6]. The number of elderly patients being referred for ECMO support when undergoing CPR has increased in recent years [7–10]. Although “age” has not been indicated to have a negative linear correlation with hospital survival in patients with ECPR [7, 11], the Good Outcome Following Attempted Resuscitation score [12] for CPR and the survival after veno-arterial-ECMO (SAVE) score [13] for ECMO both indicate that old age is a risk factor for poor hospital outcomes.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effect of interplay between age and low-flow duration on neurologic outcomes of extracorporeal cardiopulmonary resuscitation

Wang

Chi

et al. 2018

Intensive Care Med

View full text Add to dashboard Cite

PurposeCaseloads of extracorporeal cardiopulmonary resuscitation (ECPR) have increased considerably, and hospital mortality rates remain high and unpredictable. The present study evaluated the effects of the interplay between age and prolonged low-flow duration (LFD) on hospital survival rates in elderly patients to identify subgroups that can benefit from ECPR.MethodsAdult patients who received ECPR in our institution (2006–2016) were classified into groups 1, 2, and 3 (18–65, 65–75, and > 75 years, respectively). Data regarding ECPR and adverse events during hospitalization were collected prospectively. The primary end point was favorable neurologic outcome (cerebral performance category 1 or 2) at hospital discharge.ResultsIn total, 482 patients were divided into groups 1, 2, and 3 (70.5%, 19.3%, and 10.2%, respectively). LFDs were comparable among the groups (40.3, 41.0, and 44.3 min in groups 1, 2, and 3, P = 0.781, 0.231, and 0.382, respectively). Favorable neurologic outcome rates were nonsignificantly lower in group 3 than in the other groups (27.6%, 24.7%, and 18.4% for group 1, 2, and 3, respectively). Subgroup analysis revealed that the favorable neurologic outcome rates in group 1 were 36.7%, 25.4%, and 13.0% for LFDs of < 30, 30–60, and > 60 min, respectively (P = 0.005); in group 2, they were 32.1%, 21.2%, and 23.1%, respectively (P = 0.548); in group 3 they were 25.0%, 20.8%, and 0.0%, respectively (P = 0.274).ConclusionOn emergency consultation for ECPR, age and low-flow duration should be considered together to predict neurologic outcome.Electronic supplementary materialThe online version of this article (10.1007/s00134-018-5496-y) contains supplementary material, which is available to authorized users.

show abstract

Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of interplay between age and low-flow duration on neurologic outcomes of extracorporeal cardiopulmonary resuscitation

Wang

Chi

et al. 2018

Intensive Care Med

View full text Add to dashboard Cite

show abstract

“…We analyzed data from the Japanese Association for Acute Medicine Out‐of‐Hospital Cardiac Arrest (JAAM‐OHCA) registry, a prospective, multicenter cohort study, for patients registered between June 2014 and December 2015. The design of the JAAM‐OHCA registry has been reported in more detail elsewhere . Briefly, the JAAM‐OHCA registry enrolls 73 hospitals in Japan that have an emergency department (Fig.…”

Section: Methodsmentioning

confidence: 99%

Impact of type of emergency department on the outcome of out‐of‐hospital cardiac arrest: a prospective cohort study

Kaneda

Yagi

Todani

et al. 2019

Acute Medicine & Surgery

Self Cite

View full text Add to dashboard Cite

Aim To assess whether the outcomes of out‐of‐hospital cardiac arrest (OHCA) differ between patients treated at tertiary or secondary emergency medical facilities. Methods Data from the Japanese Association for Acute Medicine Out‐of‐Hospital Cardiac Arrest (JAAM‐OHCA) registry between June 2014 and December 2015 were analyzed and compared between patients treated at tertiary (tertiary group) and secondary (secondary group) emergency medical facilities. The primary outcome of this study was a favorable neurological outcome at 1 and 3 months after OHCA, defined as a Glasgow–Pittsburgh cerebral performance category of 1 or 2. Results Between June 2014 and December 2015, a total of 13,491 patients with OHCA were registered in the JAAM‐OHCA registry. Of these, 12,836 were eligible in the present analysis, with 11,583 in the tertiary group and 1,253 in the secondary group. The proportions of patients with favorable neurological outcomes in the tertiary group were significantly higher than those in the secondary group at 1 (4.7% versus 2.0%, P < 0.001) and 3 (3.5% versus 1.6%, P < 0.001) months after OHCA. Even after adjusting for baseline characteristics of patients, treatment at a tertiary emergency medical facility was independently associated with favorable neurological outcomes at 1 (odds ratio, 2.856, 95% confidence interval, 1.429–5.710; P = 0.003) and 3 (odds ratio, 2.462, 95% confidence interval, 1.203–5.042; P = 0.014) months after OHCA. Conclusion The neurological outcomes of patients with OHCA treated at tertiary emergency medical facilities were better than those of patients treated at secondary emergency medical facilities.

show abstract

“…We undertook this study to identify the diagnostic accuracy of speci c clinical parameters through a retrospective analysis of the JAAM-OHCA Registry [15], a multicenter, prospective nationwide database that includes pre-hospital information, in-hospital information, and outcome among OHCA patients transported to emergency departments in Japan. Details about this registry have been previously reported [15,16]. The JAAM-OHCA Registry was established in 2014 by the organizing committee of the registry to improve therapeutic strategy, emergency medical systems, and patient outcome.…”

Section: Study Design and Settingsmentioning

confidence: 99%

Predictive accuracy of biomarkers for survival among cardiac arrest patients with hypothermia: A prospective observational cohort study in Japan

Okada

Irisawa

Yoshiya

et al. 2020

Preprint

Self Cite

View full text Add to dashboard Cite

Background: There is little limited information on the predictive accuracy of commonly used predictors, such as lactate, pH or serum potassium for the survival among out-of-hospital cardiac arrest (OHCA) patients with hypothermia. This study aimed to identify the predictive accuracy of these biomarkers for survival among OHCA patients with hypothermia.Methods: In this retrospective study, we analyzed the data from a multicenter, prospective nationwide registry among OHCA patients transported to emergency departments in Japan (the JAAM-OHCA Registry). We included all adult (≥18 years) OHCA patients with hypothermia (≤32.0°C) who were registered from June 2014 to December 2017 and whose blood test results on hospital arrival were recorded. We calculated the predictive accuracy of pH, lactate, and potassium for 1-month survival.Results: Of the 34,754 patients in the JAAM-OHCA database, we included 754 patients from 66 hospitals. The 1-month survival was 5.8% (44/754). The areas under the curve of the predictors and 95% confidence interval were as follows: pH 0.829 [0.767–0.877] and lactate 0.843 [0.793–0.882]. On setting the cutoff points of 6.9 in pH and 120 mg/dL (13.3 mmol/L) in lactate, the predictors had a high sensitivity (lactate: 0.91; pH 0.91) and a low negative likelihood ratio (lactate: 0.14; pH 0.13), which are suitable to exclude survival to 1 month. Furthermore, in additional analysis that included only the patients with potassium values available, a cutoff point of 7.0 (mmol/L) for serum potassium had high sensitivity (0.96) and a low negative likelihood ratio (0.09).Conclusion: This study indicated the predictive accuracy of serum lactate, pH, and potassium for 1-month survival among adult OHCA patients with hypothermia. These biomarkers may help define a more appropriate resuscitation strategy. pH 6.9 and lactate 120 mg/dL can predictively rule out 1-month survival.

show abstract

The profile of Japanese Association for Acute Medicine – out‐of‐hospital cardiac arrest registry in 2014–2015

Cited by 92 publications

References 13 publications

Effect of interplay between age and low-flow duration on neurologic outcomes of extracorporeal cardiopulmonary resuscitation

Effect of interplay between age and low-flow duration on neurologic outcomes of extracorporeal cardiopulmonary resuscitation

Impact of type of emergency department on the outcome of out‐of‐hospital cardiac arrest: a prospective cohort study

Predictive accuracy of biomarkers for survival among cardiac arrest patients with hypothermia: A prospective observational cohort study in Japan

Contact Info

Product

Resources

About