Intern. Med. volume 35, issue 10, P815-820 1996 DOI: 10.2169/internalmedicine.35.815 View full text
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Tetsuya NAKADA, Hiromitsu SATO, Fuyuhiko INOUE, Fumi MIZOROGI, Kazuo NAGAYAMA, Teruji TANAKA

Abstract: Cancers producing colony-stimulating factors and associated with marked leukocytosis are relatively rare. Wereport here a case of a thyroid cancer producing both granulocyte colonystimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF). A 72-year-old womanhad a thyroid carcinoma with significant neutrophilia and eosinophilia without any evidence of infection. The serum concentrations of both G-CSFand GM-CSF were elevated significantly in this patient, which might have induced …

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