volume 345, issue 21, P1576-1577 2001
DOI: 10.1056/nejm200111223452116
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Abstract: 1 compared the effects of early invasive and conservative strategies in patients with acute coronary syndromes. Two potential biases were not discussed in their report.First, the definitions of myocardial infarction are not provided in the report, in the article outlining the study protocol, 2 or in the article cited as providing "standard TIMI definitions." 3 One must consult the TIMI 11B trial, 4 whose results were published in 1999, for these definitions. For patients who had undergone percutaneous translu…

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