Mariea A. Brady, Sureshan Sivananthan, Vivek Mudera, Qin Liu, Joerg Wiltfang, Patrick H. Warnke
Abstract:The impaired temporomandibular joint might be the first to benefit from applied tissue engineering techniques because it is small and tissue growth in larger amounts is challenging. Bone and cartilage require different competing environmental conditions to be cultivated in vitro. But coupling both the osteogenic and cartilaginous pathways of mesenchymal stem cell differentiation in homeostasis will be a key essential to grow osteochondral constructs or even the first biological joint replacement in the future.…
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