The Preventive Effect of Ethanolic Extract of Rome Beauty Apple Peel (Malus sylvestrys Mill) towards Protease Activity and Jejunal Histopathology of Rat (Rattus norvegicus) Exposed to Lead Acetate
Abstract:The exposure of lead to body can be through inhalation, digestion and adsorption. Lead intoxication can lead to jejuna damages and increase protease activity due to reactive oxygen species (ROS) production. Apple peel extract contains flavonoids that can scavenge ROS. This research aims to investigate the effect of ethanolic extract of Rome Beauty apple peel to protease activity and jejuna histological feature of rat exposed to lead acetate. This research used 20 rats, that divided into 5 treatment groups, whi… Show more
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