The prevalence of hypertension and metabolic clustering (hyperlipidemia and hyperinsulinemia) in healthy older adults

Lattanzio, Chastity N.; Petrella, Robert J.

doi:10.1016/s0895-7061(00)00509-4

Cited by 4 publications

(3 citation statements)

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“…Hyperlipidaemia and diabetes are other common risk factors for developing hypertension . They often cluster in same individuals and mutually affect the incidence of each other.…”

Section: Discussionmentioning

confidence: 99%

Risk of hypertension after hysterectomy: a population‐based study

Ding

Tsai

Hsu

et al. 2018

BJOG

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Hysterectomy is one of the most common surgeries for women with benign uterine disease. Hysterectomy may lead to a sudden decline in the production of sex hormone (estrogen and progesterone), which is responsible for vessel wall endothelial dysfunction leading to hardening of arteries and subsequent hypertension. However, the association between hysterectomy and risk of hypertension remains controversial. This study investigated whether premenopausal women have an elevated risk of hypertension after hysterectomy. This study employed the Taiwan National Health Insurance Research Database to identify 6674 women 30-49 years old who had a hysterectomy between 2000 and 2013, and a comparison group of 26 696 women who did not have a hysterectomy matched by age. Women in both the groups had no hypertension at baseline (recruiting date or within 1 year after recruiting date). By the end of 2013, we found that 1196 (17.9%) and 3613 (13.5%) women had developed hypertension in the hysterectomy and the comparison groups, respectively. The hypertension incidence was 1.4-fold greater in the hysterectomy group than in the control group (27.8 versus 20.2/1000 person-years).

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“…Hyperlipidaemia and diabetes are other common risk factors for developing hypertension . They often cluster in same individuals and mutually affect the incidence of each other.…”

Section: Discussionmentioning

confidence: 99%

Risk of hypertension after hysterectomy: a population‐based study

Ding

Tsai

Hsu

et al. 2018

BJOG

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show abstract

“…High cholesterol levels can be very damaging to people’s health, causing various severe health problems [ 3 ]. Alternatively, hyperlipidemia, a chronic metabolic disorder, is characterized by abnormalities in lipid and lipoprotein metabolism, triggering many complications, such as atherosclerosis and hypertension [ 4 ]. High-fat diet (HFD)-induced hyperlipidemia is usually associated with high levels of total cholesterol, triacylglycerols, and low-density lipoprotein (LDL), but a low level of high-density lipoprotein (HDL) [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Lipolytic Postbiotic from Lactobacillus paracasei Manages Metabolic Syndrome in Albino Wistar Rats

et al. 2021

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The current study investigates the capacity of a lipolytic Lactobacillus paracasei postbiotic as a possible regulator for lipid metabolism by targeting metabolic syndrome as a possibly safer anti-obesity and Anti-dyslipidemia agent replacing atorvastatin (ATOR) and other drugs with proven or suspected health hazards. The high DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS [2,2′-azino-bis (3-ethyl benzothiazoline-6-sulphonic acid)] scavenging activity and high activities of antioxidant enzyme such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-px) of the Lactobacillus paracasei postbiotic (cell-free extract), coupled with considerable lipolytic activity, may support its action against metabolic syndrome. Lactobacillus paracasei isolate was obtained from an Egyptian cheese sample, identified and used for preparing the postbiotic. The postbiotic was characterized and administered to high-fat diet (HFD) albino rats (100 and 200 mg kg−1) for nine weeks, as compared to atorvastatin (ATOR; 10 mg kg−1). The postbiotic could correct the disruption in lipid metabolism and antioxidant enzymes in HFD rats more effectively than ATOR. The two levels of the postbiotic (100 and 200 mg kg−1) reduced total serum lipids by 29% and 34% and serum triglyceride by 32–45% of the positive control level, compared to only 25% and 35% in ATOR’s case, respectively. Both ATOR and the postbiotic (200 mg kg−1) equally decreased total serum cholesterol by about 40% and 39%, while equally raising HDL levels by 28% and 30% of the positive control. The postbiotic counteracted HFD-induced body weight increases more effectively than ATOR without affecting liver and kidney functions or liver histopathology, at the optimal dose of each. The postbiotic is a safer substitute for ATOR in treating metabolic syndrome.

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“…In recent years, metabolic syndromes increase rapidly both in developed and developing countries due to the changes in the lifestyle and dietary habitsof people [1]. Hyperlipidemia is a chronic metabolic disorder characterized by abnormalities in lipid and lipoprotein metabolism, which can cause many complications, such as hypertension and atherosclerosis [2]. An imbalance between oxidative stress and antioxidative defense mechanisms can result in cell and tissue damage by the free radical chain reaction of lipid peroxidation and can accelerate hyperlipidemia complications.…”

Section: Introductionmentioning

confidence: 99%

Radical Scavenging and Hypolipidemic Activity of Aqueous Extracts from Labadou (A Traditional Fermented Soybean Food of Southern China)

Lü

Yuan

et al. 2011

AMR

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Labadou was prepared according to the traditional technology of Southern China and its aqueous extract (AEL) was obtained. The oxygen radical scavenging capacity of AEL was assessed. The hypolipidemic effects in hyperlipidemic rats of AEL were investigated through designed sequential trials and by measuring serum lipid parameters. Results showed that AELexhibited significant ( p < 0.01) scavenging potencies on superoxide and hydroxyl at a concentration of 10 mg/ml. It was also found that AEL could significantly reduce serum total cholesterol (TC) and triglyceride (TG) concentrations and at same time markedly increased the high density lipoprotein cholesterol (HDL-C) levels after 3 weeks treatment in tested rats. These results showed that Labadou had an excellent hypolipidemic activity and the peptides of low molecular mass from Labadou were one of the possible principles of bioactivity.

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The prevalence of hypertension and metabolic clustering (hyperlipidemia and hyperinsulinemia) in healthy older adults

Cited by 4 publications

References 0 publications

Risk of hypertension after hysterectomy: a population‐based study

Risk of hypertension after hysterectomy: a population‐based study

Lipolytic Postbiotic from Lactobacillus paracasei Manages Metabolic Syndrome in Albino Wistar Rats

Radical Scavenging and Hypolipidemic Activity of Aqueous Extracts from Labadou (A Traditional Fermented Soybean Food of Southern China)

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