The prevalence of erectile dysfunction in men visiting outpatient clinics

Haczyński, Józef; Lew-Starowicz, Zbigniew; Darewicz, Barbara; Krajka, K; Piotrowicz, Radosław; Ciesielska, Beata

doi:10.1038/sj.ijir.3901435

Cited by 19 publications

(13 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Using an erectile rigidity VAS, the mean rigidity was 43 (22, 39-47, 0-80)%. In all, 90% of patients had IIEF EFD scores available; the mean score at presentation was 15 (4,(13)(14)(15)(16)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23) 16). Cavernosograms taken in the six patients with vasculogenic ED showed crural venous leak in five.…”

Section: Resultsmentioning

confidence: 99%

“…In the present study there was a prolonged delay from the onset of ED to comprehensive evaluation and treatment (mean 22.6 months), regardless of the cause of ED (psychogenic or vasculogenic). A delay in seeking treatment is also common among older men; at presentation, < 10% have ED of < 1 year in duration, a third has ED lasting 1-2 years and most seek treatment after > 2 years of ED [10]. Heruti et al [11] showed that even after sexual dysfunction is diagnosed only a minority of young men seek evaluation and treatment.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Vasculogenic erectile dysfunction in teenagers: a 5‐year multi‐institutional experience

et al. 2009

View full text Add to dashboard Cite

assessed males aged ≤ 19 years presenting with ED. The review of these databases focused on demographic characteristics, risk factors for ED, erectile function, results of vascular evaluation, and the causes of ED. RESULTSIn all, 40 males aged 14-19 years were identified. The mean (range) duration of ED at presentation was 22.6 (4-84) months. The major risk factors for ED were antecedent perineal trauma (37%) and penile trauma or surgery (15%). The mean ( SD ) International Index of Erectile Function 'erectile function' domain score was 15 (4). Information obtained by history taking was not predictive of the cause of ED. Vascular studies were performed in 62% of the patients and 48% of these patients were found to have an underlying vascular pathology; 42% of the latter group were found to be possible candidates for surgical intervention and another 16% needed further angiographic evaluation. CONCLUSIONED in teenagers should not be routinely categorized as psychogenic without an adequate vascular evaluation, as a significant percentage have abnormal erectile haemodynamics consistent with vasculogenic ED.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Vasculogenic erectile dysfunction in teenagers: a 5‐year multi‐institutional experience

et al. 2009

View full text Add to dashboard Cite

show abstract

“…Worldwide it is estimated that over 100,000,000 men are affected [1]. It is expected that between 1995 and 2025 the prevalence of ED worldwide will have increased by more than 110% [2].…”

Section: Epidemiologymentioning

confidence: 99%

Erectile Dysfunction

Wylie¹

2008

Advances in Psychosomatic Medicine

View full text Add to dashboard Cite

Erectile dysfunction is a common problem affecting sexual function in men. Approximately one in 10 men over the age of 40 is affected by this condition and the incidence is age related. Erectile dysfunction is a sentinel marker for several reversible conditions including peripheral and coronary vascular disease, hypertension and diabetes mellitus. Endothelial dysfunction is a common factor between the disease states. Concurrent conditions such as depression, late-onset hypogonadism, Peyronie's disease and lower urinary tract symptoms may significantly worsen erectile function, other sexual and relationship issues and penis dysmorphophobia. A focused physical examination and baseline laboratory investigations are mandatory. Management consists of initiating modifiable lifestyle changes, psychological and psychosexual/couples interventions and pharmacological and other interventions. In combination and with treatment of concurrent comorbid states, these interventions will often bring about successful resolution of symptoms and avoid the need for surgical interventions.

show abstract

“…Erectile dysfunction (ED) is a major men’s health issue affecting 30 million men in the United States alone and this number is expected to increase two-fold in the next 20 years with the aging population (Haczynski et al, 2006). Normal erectile function requires that a number of different cell types and systems work in concert.…”

Section: Introductionmentioning

confidence: 99%

Recombinant PAI-1 therapy restores myoendothelial junctions and erectile function in PAI-1-deficient mice

et al. 2014

View full text Add to dashboard Cite

SUMMARY Myoendothelial junctions are specialised projections of cell:cell contact through the internal elastic lamina between endothelial cells and vascular smooth muscle cells. These junctions allow for endothelial cells and vascular smooth muscle cells to make direct membrane apposition and are involved in cell:cell communication. In the current study, we evaluated for the presence of myoendothelial junctions in murine corporal tissue and used plasminogen activator inhibitor (PAI)-1 deficient mice, that lack myoendothelial junctions, to determine if myoendothelial junctions affect erectile function. Transmission electron microscopy demonstrated the presence of myoendothelial junctions in corporal tissue of wild type mice and confirmed decreased junction numbers in the tissue of PAI-1−/− mice. A potential role for myoendothelial junctions in tumescence was established; in that, PAI-1−/− mice demonstrated a significantly longer time to achieve maximal intracavernous pressure. Treatment of PAI-1−/− mice with recombinant PAI-1 restored the number of myoendothelial junctions in the corporal tissue and also induced a significant decrease in time to maximal corporal pressures. Myoendothelial junctions were similarly identified in human corporal tissue. These results suggest a critical role for myoendothelial junctions in erectile pathophysiology and therapies aimed at restoring myoendothelial junction numbers in the corporal tissue may provide a novel therapy for erectile dysfunction.

show abstract

The prevalence of erectile dysfunction in men visiting outpatient clinics

Cited by 19 publications

References 16 publications

Vasculogenic erectile dysfunction in teenagers: a 5‐year multi‐institutional experience

Vasculogenic erectile dysfunction in teenagers: a 5‐year multi‐institutional experience

Erectile Dysfunction

Recombinant PAI-1 therapy restores myoendothelial junctions and erectile function in PAI-1-deficient mice

Contact Info

Product

Resources

About