The Prevalence of Diagnosed Cutaneous Manifestations during Ambulatory Diabetes Visits in the United States, 1998–2002

Wang, Y. Richard; Margolis, David J.

doi:10.1159/000091249

Cited by 17 publications

(14 citation statements)

References 30 publications

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“…Different gender ratio, diabetes type, duration of disease, age and the degree/extent of accessibility to appropriate medical care may be some of the factors underlying the difference observed between these studies. Wang and Margolis [16 ]have recently shown in a controlled study that chronic skin ulcers, bacterial and fungal skin infections are more frequently diagnosed in outpatient diabetics in the USA. They could not verify the association of other skin conditions with diabetes and attributed it partly to potential underdiagnosis and underreporting[.…”

Section: Discussionmentioning

confidence: 99%

Dermopathy and Retinopathy in Diabetes: Is There an Association?

Abdollahi

Daneshpazhooh²,

Amirchaghmaghi

et al. 2007

Dermatology

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Background/Aims: Diabetic dermopathy is the most common cutaneous marker of diabetes mellitus presenting as single or multiple well-demarcated brown atrophic macules, predominantly on the shins. Although diabetic dermopathy and diabetic retinopathy are both considered by some authors as manifestations of diabetic microangiopathy, only a few studies are published about their possible association. Our purpose was to investigate the association of diabetic dermopathy and diabetic retinopathy. Methods: We conducted a cross-sectional study in an outpatient diabetes clinic during a 6-month period. One-hundred and eighty-one consecutive patients (8 cases of insulin-dependent diabetes mellitus and 173 cases of non-insulin-dependent diabetes mellitus) were examined for the presence of diabetic dermopathy and diabetic retinopathy. Results: Forty-seven (26%) showed diabetic dermopathy and 68 patients (37.6%) suffered from diabetic retinopathy. The frequency of retinopathy in patients with diabetic dermopathy (44%; 30 cases) was significantly greater than in patients without dermopathy (15%; 17 cases; p < 0.0001). Retinopathy showed a statistically significant association with dermopathy [odds ratio (OR): 3.60; 95% confidence interval (CI): 1.53–8.44; p = 0.003] and diabetes duration (OR: 3.36; 95% CI: 1.67–6.77; p = 0.001). Conclusion: Our study further supports that diabetic dermopathy might be used as a telltale sign of diabetic retinopathy, necessitating more intensive ophthalmologic care, especially in long-lasting diabetes.

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Section: Discussionmentioning

confidence: 99%

Dermopathy and Retinopathy in Diabetes: Is There an Association?

Abdollahi

Daneshpazhooh²,

Amirchaghmaghi

et al. 2007

Dermatology

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“…cutaneous infection, dry skin, pruritus—that can lead to major complications and are highly associated with hyperglycemia and advanced glycation end products (AGEs) [1]. …”

Section: Introductionmentioning

confidence: 99%

Skin disorders in diabetes mellitus: an epidemiology and physiopathology review

Macedo¹,

Nunes

Barreto

2016

Diabetol Metab Syndr

131

107

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Skin disorders, usually neglected and frequently underdiagnosed among diabetic patients, are common complications and encounter a broad spectrum of disorders in both type 1 and type 2 diabetes mellitus (DM)—e.g. cutaneous infection, dry skin, pruritus. Skin disorders are highly associated with increased risk of important outcomes, such as skin lesions, ulcerations and diabetic foot, which can lead to major complications and revolve around multifactorial factors besides hyperglycemia and advanced glycation end products. Although diabetic’s skin disorders are consistent in the literature, there is limited data regarding early-stage skin disorders in DM patients. Disease control, early-stage treatment (e.g. skin hydration, orthotic devices) and awareness can reduce morbidity of DM patients. Thus, better understanding of the burden of skin disorders in DM patients may raise awareness on prevention and management. Therefore, the aim of this study is to perform a literature review to evaluate the main clinical characteristics and complications of skin disorders in diabetic’s patients. Additionally, physiopathology early-stage skin disorders and dermocosmetic management were also reviewed.

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“…1 The frequency of dermatological disorders during the course of diabetes has been reported to range from 30.0 to 91.2%. 2-4 …”

Section: Introductionmentioning

confidence: 99%

Relation between cutaneous and extracutaneous complications in pediatric patients with type 1 diabetes

Kamel

Elhenawy

Saudi

2018

Dermato-Endocrinology

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Background: The relationship between cutaneous and extracutaneous complications in pediatric patients with type 1 diabetes is unclear. Objective: The objective of the current study is to investigate the relationship between skin disorders and diabetic microangiopathic changes in pediatric and adolescent patients with type 1 diabetes. Patients and methods: Eighty patients with type 1 diabetes and 50 healthy controls were enrolled in the study. All recruited patients were followed up monthly for a total period of 12 month. Monthly visit included thorough clinical examination with system review, as well as whole-body cutaneous examination. HbA1c was assessed every 3 month. Twenty-four hours urine was collected for measurement of urinary albumin. Results: Fifty percent of the screened diabetic cohort had diabetic nephropathy (DN). The overall prevalence of cutaneous lesion among the studied diabetic cohort was high (72.5%), with cutaneous infections (40%) and xerosis (30%) being the most prevalent. The frequency of cutaneous infections, xerosis and rubeosis faciei was higher in patients with nephropathy than in those without nephropathy. Conclusion: cutaneous affection in patients with diabetes may be a clue to the presence of associated microangioapthic complications. The significant association between diabetic nephropathy and cutaneous lesions support the concept that cutaneous lesion in diabetes is a reflection of diabetic angiopathy, highlighting the importance of identifying patients at risk of other microvascular complications.

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The Prevalence of Diagnosed Cutaneous Manifestations during Ambulatory Diabetes Visits in the United States, 1998–2002

Cited by 17 publications

References 30 publications

Dermopathy and Retinopathy in Diabetes: Is There an Association?

Dermopathy and Retinopathy in Diabetes: Is There an Association?

Skin disorders in diabetes mellitus: an epidemiology and physiopathology review

Relation between cutaneous and extracutaneous complications in pediatric patients with type 1 diabetes

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