The prevalence of asthma and atopy in schoolchildren from Porto Alegre, Brazil, has plateaued

Schuh, Camila; Fritscher, Leandro Genehr; Fritscher, Carlos Cézar

doi:10.1016/j.rmed.2015.01.014

Cited by 5 publications

(11 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other studies, however, have shown that trends in the prevalence of asthma vary across Brazilian capitals, the prevalence of asthma increasing considerably each year in some cities, such as Florianópolis, (16) and remaining stable in others, such as Porto Alegre. (17) Data on the prevalence of common chronic diseases such as asthma and obesity play an important role in guiding health policies and providing the basis for the development of educational interventions and preventive measures. Therefore, the objective of the present study was to estimate the prevalence of respiratory symptoms and asthma, according to BMI, as well as to evaluate factors associated with physician-diagnosed asthma, in individuals ≥ 40 years of age.…”

Section: Introductionmentioning

confidence: 99%

“…Few studies have examined trends in the prevalence of asthma in Brazil. 15 - 17 In a study conducted in Brazil and examining 2013 Brazilian National Health Survey data for 60,202 adults (in the 18- to 49-year age bracket), the prevalence of physician-diagnosed asthma was found to be 4.4%. 15 In addition, the study examined temporal trends in the prevalence of asthma, which was found to have remained stable in 1998, 2003, and 2008.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Body mass index, asthma, and respiratory symptoms: a population-based study

et al. 2020

View full text Add to dashboard Cite

Objective: To estimate the prevalence of respiratory symptoms and asthma, according to body mass index (BMI), as well as to evaluate factors associated with physician-diagnosed asthma, in individuals ≥ 40 years of age. Methods: This was a population-based cross-sectional study conducted in Florianópolis, Brazil, with probability sampling. Data were collected during home visits. Demographic data were collected, as were reports of physician-diagnosed asthma, respiratory symptoms, medications in use, and comorbidities. Anthropometric measurements were taken. Individuals also underwent spirometry before and after bronchodilator administration. Individuals were categorized as being of normal weight (BMI < 25 kg/m2), overweight (25 kg/m2 ≥ BMI < 30 kg/m2), or obese (BMI ≥ 30 kg/m2). Results: A total of 1,026 individuals were evaluated, 274 (26.7%) were of normal weight, 436 (42.5%) were overweight, and 316 (30.8%) were obese. The prevalence of physician-diagnosed asthma was 11.0%. The prevalence of obesity was higher in women (p = 0.03), as it was in respondents with ≤ 4 years of schooling (p < 0.001) or a family income of 3-10 times the national minimum wage. Physician-diagnosed asthma was more common among obese individuals than among those who were overweight and those of normal weight (16.1%, 9.9%, and 8.0%, respectively; p = 0.04), as were dyspnea (35.5%, 22.5%, and 17.9%, respectively; p < 0.001) and wheezing in the last year (25.6%, 11.9%, and 14.6%, respectively; p < 0.001). These results were independent of patient smoking status. In addition, obese individuals were three times more likely to report physician-diagnosed asthma than were those of normal weight (p = 0.005). Conclusions: A report of physician-diagnosed asthma showed a significant association with being ≥ 40 years of age and with having a BMI ≥ 30 kg/m2. Being obese tripled the chance of physician-diagnosed asthma.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Body mass index, asthma, and respiratory symptoms: a population-based study

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The prevalence of atopy in childhood has increased since the latter part of the 20th century [7, 8]. And there are very different atopy rates that have been reported in different regions [9, 10]. Studies have reported atopy rates that range from 20.5% in Germany [11] to 57.7% in Hong Kong [12].…”

Section: Introductionmentioning

confidence: 99%

“…Studies have reported atopy rates that range from 20.5% in Germany [11] to 57.7% in Hong Kong [12]. The wide range of prevalence of atopy may due to the international variability and regional differences [9,10]. Atopy is associated with an aberrant response to allergens through IgE production by antigen-specific Th2 cells and B cells [13].…”

Section: Introductionmentioning

confidence: 99%

Atopy in children with juvenile systemic lupus erythematosus is associated with severe disease

Guo

Zhou

et al. 2017

PLoS ONE

View full text Add to dashboard Cite

The influence of co-existing atopy on the prognosis of juvenile systemic lupus erythematosus (JSLE) was assessed in this study. Patients diagnosed with JSLE between October 2005 and April 2016 were enrolled in a prospective study and followed up for 2 years. Management of patients was evaluated using the systemic lupus erythematosus disease activity index 2000 (SLEDAI-2K) score and laboratory variables. Eighty JSLE patients were enrolled at diagnosis and divided into those with (n = 35) and without (n = 45) atopy. When compared with the non-atopic group, atopic patients showed higher SLEDAI-2K score at disease onset (16.09 vs. 11.18), higher erythrocyte sedimentation rate (52.89 vs. 38.27 mm/h), higher percentage of total B-cells (25.85 vs. 19.51%), lower percentage (7.26 vs. 9.03%) and cytotoxicity (9.92 vs. 11.32%) of natural killer cells, and lower complement C3 (0.51 vs. 0.69 g/L) (all p<0.05). At 1, 3, 6, 12, 18, and 24 months, JSLE patients with atopy reached higher SLEDAI-2K score and lower ΔSLEDAI-2K improvement rate (at 1 month, 8.34 vs. 4.71 and 43.63 vs. 57.95%, respectively; at 3 months, 8.57 vs. 2.62 and 48.39 vs. 75.10%, respectively; at 6 months, 6.91 vs. 2.38 and 53.59 vs. 77.26%, respectively; at 12 months, 4.71 vs. 1.80 and 69.54 vs. 84.10%, respectively; at 18 months, 4.66 vs. 2.02 and 68.14 vs. 82.93%, respectively; at 24 months, 8.57 vs. 2.62 and 70.00 vs. 81.88%, respectively; all p<0.05). During the 24 months of follow-up, the total number of disease flares was higher in JSLE patients with co-existing atopy (3.77 vs. 1.51, p<0.05), and the atopic group needed much more time to reach the stable condition of the disease (6.88 vs. 4.65 months, p<0.05). JSLE patients combined with co-existing atopy had more severe disease at diagnosis and poorer outcomes than JSLE patients without atopy.

show abstract

Food allergy in infants assessed in two German birth cohorts 10 years after the EuroPrevall Study

Röhrl

Brandstetter

Siziba

et al. 2021

Pediatric Allergy Immunology

View full text Add to dashboard Cite

Background The prevalence of food allergies (FA) in children increased rapidly at the turn of the century. The EuroPrevall study identified Germany as a country with very high prevalence of FA at that time. Using two large German birth cohorts, we provide an update of the status quo 10 years later. Methods KUNO Kids and Ulm SPATZ Health studies are two ongoing prospective birth cohorts. Information on FA was obtained by questionnaires at birth and after 6, 12, and 24 months. Univariable and multivariable logistic regression analyses were performed to investigate risk factors during pregnancy, birth, and early childhood. Results In 1139 and 1006 children from KUNO Kids and SPATZ, the point prevalence of parent‐reported FA symptoms at the ages of 1 and 2 years was 13.2% (95% CI: 11.2–15.2) and 13.9% (95% CI: 11.5–17.2) in KUNO Kids. Doctor's diagnosed FA at 1 and 2 years was 2.4% (95% CI: 1.6–3.4) and 2.7% (95% CI: 1.2–4.3) in KUNO Kids and 2.3% (95% CI: 1.3–3.6) and 3% (95% CI: 2.0–4.5) in SPATZ. Cow's milk and citrus fruits were most frequently suspected by parents to cause FA symptoms. Atopy in the child was associated with a higher frequency of FA at any time, whereas atopy in first‐degree relatives was only associated with FA at year 1. Smoke exposure during pregnancy was a risk for FA at age 2. Conclusion The prevalence of food allergy seems to have plateaued in the last 10 years in Germany. FA is often suspected by parents but only rarely diagnosed by oral food challenge. Risk factor analysis may help to establish personalized health approaches.

show abstract

The prevalence of asthma and atopy in schoolchildren from Porto Alegre, Brazil, has plateaued

Abstract: In the last decade the prevalence of atopy and lifetime asthma has plateaued, while the prevalence of current asthma fell.

Cited by 5 publications

References 14 publications

Body mass index, asthma, and respiratory symptoms: a population-based study

Body mass index, asthma, and respiratory symptoms: a population-based study

Atopy in children with juvenile systemic lupus erythematosus is associated with severe disease

Food allergy in infants assessed in two German birth cohorts 10 years after the EuroPrevall Study

Contact Info

Product

Resources

About