The Present Status of the Treatment of Chronic Ulcerative Colitis with Steroid Hormones

Rosenak, Bernard D.; Pickett, R.D.; Vactor, Helen D. Van; Hammond, James M.; Healey, Robert J.; Moser, Rollin H.

doi:10.1016/s0016-5085(58)80032-3

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1960

1967

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Cited by 12 publications

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“…Bargen drew attention to this danger in 1955, andBrooke (1956) reported samples of colonic disintegration which were claimed only to occur in steroid-treated patients. Several other reports emphasize the dangers of steroid therapy for colitic patients (Rosenak et al 1958), Keifer 1960, Bruce & Cole 1962. Other authors state with equal emphasis that steroids do not increase the risk of perforation (Goldgraber et al 1957, Truelove & Witts 1959, Smith et al 1962, Spencer et al 1962, Korelitz & Lindner 1964.…”

Section: Discussionmentioning

confidence: 99%

Intraperitoneal Perforation of the Colon in Ulcerative Colitis [Abridged]

Watkinson

et al. 1965

Proceedings of the Royal Society of Medicine

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S Section ofProctology 713 rather than upon half of them while they are desperately ill. Summary(1) The outcome of any attack of colitis depends on the severity of the attack, the extent of disease and the age of the patient at the time.(2) If surgery is to be used in a severe attack, it should be in the early stages. (3) Total involvement of the colon implies such a poor prognosis that prophylactic proctocolectomy may be justified in these patients. It may also be justified in patients over 60 even if the large bowel is not totally involved.

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