“…The time interval for defining prolonged MV or extubation failure has yet to be established, ranging from 6 to 48 h in recent studies (6)(7)(8)(9) and from 2 to 7 days in older studies (10,11). The maintenance of patients on MV for a prolonged length of time can cause complications such as development of oxygen toxicity, larynx injuries, tracheal stenosis, selective intubation, sinusitis, barotrauma, reduced cardiac output, pneumonia, and psychological problems (12).…”