The Potential of Mangifera indica L. Peel Extract to Be Revalued in Cosmetic Applications

Abstract

The constant growth of the cosmetic industry, together with the scientific evidence of the beneficial properties of phytochemicals, has generated great interest in the incorporation of bioactive extracts in cosmetic formulations. This study aims to evaluate the bioactive potential of a mango peel extract for its incorporation into cosmetic formulations. For this purpose, several assays were conducted: phytochemical characterization; total phenolic content (TPC) and antioxidant potential; free-radical scavenging capacity; and skin aging-related enzyme inhibition. In addition, the extract was incorporated into a gel formulation, and a preliminary stability study was conducted where the accelerated (temperature ramp, centrifugation, and heating/cooling cycles) and long-term (storage in light and dark for three months) stability of the mango peel formulations were evaluated. The characterization results showed the annotation of 71 compounds, gallotannins being the most representative group. In addition, the mango peel extract was shown to be effective against the ·NO radical with an IC50 of 7.5 mg/L and against the hyaluronidase and xanthine oxidase enzymes with IC50 of 27 mg/L and 2 mg/L, respectively. The formulations incorporating the extract were stable during the stability study. The results demonstrate that mango peel extract can be a by-product to be revalorized as a promising cosmetic ingredient.

Bioactive Compounds and Potential Health Benefits through Cosmetic Applications of Cherry Stem Extract

“…To obtain the cherry stem extract, the same methodology was used as in García et al [17]. The extracts obtained from the cherry stem had a caramel-like appearance and texture with a dark brown shade.…”

“…The chromatographic and mass spectrometry conditions and parameters were applied following the previously optimized method [17].…”

“…This encompassed multiple data processing steps, including background noise detection, ADAP chromatogram builder, ADAP chromatogram deconvolution, isotope grouping, and alignment. The specific parameters used in data processing were reported previously [17]. Finally, the prediction of molecular formular and chemical structures was performed with Sirius 5.8.1.…”

“…Accelerated stability tests assessed the stability of gels under harsh conditions. To carry out the accelerated stability tests, the ISO/TR 18811 "Cosmetics-Guidelines on the stability testing of cosmetic products" and the previously described methodology were followed [17,123]. For this purpose, accelerated stability was evaluated by centrifugation, temperature ramp, and heating-cooling cycles.…”

“…For example, grape stem and seed extracts, rich in polyphenols such as catechin, resveratrol, and gallic acid, have been shown to be excellent antioxidant and anti-aging agents [14,15]. It has also been observed that green tea extract and mango peel extract, rich in epigallocate-chin-3-gallate, are able to inhibit inflammatory enzymes and cytokines, and that quercetin-rich extracts such as passion fruit peel and seeds block UV-induced inflammation [16][17][18].…”