The potential influence of hormesis on evolution of resistance to herbicides

Belz, Regina G.; Carbonari, Caio Antônio; Duke, Stephen O.

doi:10.1016/j.coesh.2022.100360

Cited by 21 publications

(24 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This suggests the possibility that the genetic and physiological processes controlling glyphosate hormesis and resistance might be independent, so the selection of the former does not necessarily result in selection of the latter. Thus, if hormesis indeed favors herbicide resistance evolution, our results support the hypothesis that it does so by increasing the survival and reproduction of plants exposed to sublethal doses, which ultimately will favor a faster accumulation of resistance alleles and the transition from susceptible to resistant populations, especially in cases of nontarget‐site resistance 29,57 …”

Section: Discussionsupporting

confidence: 71%

“…There is evidence indicating that hormesis can be subject to selection and influence fitness 58–61 . It has been proposed that an important consequence of hormesis is that it could influence the evolution of more competitive weed biotypes 29,62 . Although it is not clear whether the increase in competitive ability documented here is directly related to the increase in glyphosate hormesis, selection forces present within the crop can certainly favor both processes separately and complementarily.…”

Section: Discussionmentioning

confidence: 78%

“…The treatment with sublethal doses has implications not only for control efficacy but also for evolutionary changes in weeds. For example, the stimulatory growth response that herbicides can trigger on plants at low doses, known as hormesis, has been associated with the potential evolution of herbicide resistance and with changes in competitive ability 29 . Although the physiological mechanisms of herbicide hormesis are not fully understood, there are reports of this phenomenon in multiple crop and weed species for widely used herbicides such as glyphosate 30,31 .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Changes in the herbicide sensitivity and competitive ability of Abutilon theophrasti over 28 years: Implications for hormesis and weed evolution

Ethridge

Chandra

Locke

et al. 2023

Pest Management Science

View full text Add to dashboard Cite

BACKGROUNDThe potential of weed species to respond to selection forces affecting the evolution of weedy traits such as competitive ability is poorly understood. This research characterized evolutionary growth changes in a single Abutilon theophrasti Medik. population comparing multiple generations collected from 1988 to 2016. A competition study was performed to understand changes in competitive ability, and a herbicide dose–response study was carried out to assess changes in sensitivity to acetolactate synthase‐inhibiting herbicides and glyphosate over time.RESULTSWhen grown in monoculture, A. theophrasti biomass production per plant increased steadily across year‐lines while leaf number decreased. In replacement experiments, A. theophrasti plants from newer year‐lines were more competitive and produced more biomass and leaf area than the oldest year‐line. No clear differences in sensitivity to imazamox were observed among year‐lines. However, starting in 1995, this A. theophrasti population exhibited a progressive increase in growth in response to a sublethal dose of glyphosate (52 g a.e. ha−1), with the 2009 and 2016 year‐lines having more than 50% higher biomass than the nontreated control.CONCLUSIONThis study demonstrates that weeds can rapidly evolve increased competitive ability. Furthermore, the results indicate the possibility of changes in glyphosate hormesis over time. These results highlight the importance of the role that rapid (i.e., subdecadal) evolution of growth traits might have on the sustainability of weed management strategies. © 2023 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

show abstract

Section: Discussionsupporting

confidence: 71%

Section: Discussionmentioning

confidence: 78%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Changes in the herbicide sensitivity and competitive ability of Abutilon theophrasti over 28 years: Implications for hormesis and weed evolution

Ethridge

Chandra

Locke

et al. 2023

Pest Management Science

View full text Add to dashboard Cite

show abstract

“…Three significant historical models including the threshold dose response, the linear non‐threshold (LNT) model, and hormesis model have been constructed. Hormesis describes a biphasic dose response relationship featuring stimulation at a low dose and inhibition at a high dose, 1 and has become a mainstream theory of toxicology in recent years 2,3 . Unlike the threshold or LNT models, the hormesis model can explain low‐level stress, including modest biological responses which are the opposite to the responses to high‐level stress 4,5 .…”

Section: Introductionmentioning

confidence: 99%

Hormesis effects in tomato plant growth and photosynthesis due to acephate exposure based on physiology and transcriptomic analysis

Sun

Wang

et al. 2023

Pest Management Science

View full text Add to dashboard Cite

BACKGROUND: Hormesis is a common phenomenon in toxicology described as low-dose stimulation due to a toxin which causes inhibition at a high dose. Pesticide hormesis in plants has attracted considerable research interest in recent years; however, the specific mechanism has not yet been clarified. Acephate is an organophosphorus insecticide that is used worldwide. Here, hormesis in tomato (Solanum lycopersicum L.) plant growth and photosynthesis after acephate exposure is confirmed, as stimulation occurred at low stress levels, whereas inhibition occurred after exposure to high concentrations.RESULTS: We found that low acephate concentration (5-fold lower than recommended application dosage) could enhance chlorophyll biosynthesis and stimulate photosynthesis effects, and thus improve S. lycopersicum growth. A high level of acephate (5-fold higher than recommended application dosage) stress inhibited chlorophyll accumulation, decreased photosystem II efficiency and blocked antioxidant reactions in leaves, increasing reactive oxygen species levels and damaging plant growth. Transcriptomic analysis and quantitative real-time PCR results revealed that the photosynthesisantenna proteins pathway played a crucial role in the hormesis effect, and that LHCB7 as well as LHCP from the pathway were the most sensitive to acephate hormesis. CONCLUSION: Our results showed that acephate could induce hormesis in tomato plant growth and photosynthesis, and that photosystem II and the photosynthesisantenna proteins pathway played important roles in hormesis. These results provide novel insights into the scientific and safe application of chemical pesticides, and new guidance for investigation into utilizing pesticide hormesis in agriculture.

show abstract

“…A great number of dose–response studies indicate that hormesis is a common phenomenon, occurring in numerous organisms exposed to singular or combined environmental stressors, such as pharmaceuticals, heavy metals, micro/nanoplastics, organic flame retardants, pesticides, and rare earths. − While biological responses to low exposure levels are often beneficial, exposure to doses below the no-observed-adverse-effect-level (NOAEL; hereafter subthreshold doses) does not always translate to beneficial responses. , For example, subthreshold contaminant doses can enhance the virulence of phytopathogenic microbes and promote the resistance of crop pests with significant implications for crop production. ,, Subthreshold contaminant exposures can also stimulate infectious animal/human pathogens and promote their resistance to antibiotics and other drugs, threatening long-term sustainability. Importantly, the hormetic function of common pathways that regulate cancer progress indicate that current regulatory standards may not protect adequately against cancer risks. − …”

mentioning

confidence: 99%