The Potential Effects of the Essential Oil of Coriander Seeds  on Bacterial Biofilm and Immune Cells

Hasen, Eliza

doi:10.35516/jjps.v16i2.1530

Cited by 2 publications

(1 citation statement)

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“…GraphPad Prism 5.0 was used for statistical analysis [14]. The data were presented as mean values ± standard deviation (SD).…”

Section: Discussionmentioning

confidence: 99%

Distribution of Vitamin D Status in a Group from Syrian Society

Almelli

2023

Jordan j. pharm. sci.

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Objective: The aim of this work is to study the serum levels of 25-hydroxyvitamin D3 in a sample of healthy Syrians in the city of Homs. Method: A cross-sectional study, including 690 ostensibly healthy participants, was conducted at the National Hospital of Homs. Serum levels of 25-hydroxyvitamin D3 were measured using chemiluminescent immunoassay. Results: The overall prevalence of vitamin D inadequacy (insufficiency, deficiency, and severe deficiency) in the study samples was 76.5%. Additionally, 49% of the samples had vitamin D deficiency, with 18.5% suffering from severe deficiency. Furthermore, levels of 25-hydroxyvitamin D3 in females were lower than in males (11.3±2.3 ng/ml versus 39.6±11.28 ng/ml, respectively, p < 0.0001). Veiled women had serum levels of vitamin D lower than non-veiled women, 11.3±2.5 ng/ml versus 25.5±3.2 ng/ml, respectively, p < 0.0001. Female gender and clothing style were identified as independent risk factors for vitamin D deficiency. Conclusion: The prevalence of vitamin D deficiency was very common in the study population, despite the sunny weather in Homs city most of the year. Further studies with larger groups, including other Syrian governorates, are needed to elucidate lifestyle and sociocultural behavior risk factors for vitamin D deficiency.

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“…GraphPad Prism 5.0 was used for statistical analysis [14]. The data were presented as mean values ± standard deviation (SD).…”

Section: Discussionmentioning

confidence: 99%

Distribution of Vitamin D Status in a Group from Syrian Society

Almelli

2023

Jordan j. pharm. sci.

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The effect of Jordanian essential oil from coriander seeds on antioxidant, anti-inflammatory, and immunostimulatory activities using RAW 246.7 murine macrophages

Omar,

Barakat,

Alzaghari

et al. 2024

PLoS ONE

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Coriander (Coriandrum sativum L.) is a member of the Umbelliferae/Apiaceae family and one of the well-known essential oil-containing plants, in which the seeds are used in traditional medicine, and as flavoring in food preparation. Knowing the diverse chemical components of different parts of the plant, this work aims to investigate the antioxidant, the anti-inflammatory, and the immunostimulatory modulator effects of the Jordanian C. sativum’s seed extracted essential oil (JCEO). Coriander oil extract was prepared by hydro-distillation method using the Clevenger apparatus. Different concentrations of coriander oil were examined by using DPPH radical scavenging assay, MTT assay, pro-inflammatory cytokine (Tumor Necrosis Factor-TNF-alpha) production in RAW264.7 murine macrophages in addition, scratch-wound assessment, NO level examination, Th1/Th2 assay, phagocytosis assay, and fluorescence imaging using DAPI stain were conducted. JCEO had a potential metabolic enhancer effect at a concentration of 0.3 mg/mL on cell viability with anti-inflammatory activities via increasing cytokines like IL-10, IL-4, and limiting NO, INF-γ, and TNF-α release into cell supernatant. Antioxidant activity was seen significantly at higher concentrations of JCEO reaching 98.7% when using 100mg/mL and minimally reaching 50% at 12.5mg/mL of the essential oil. Treated macrophages were able to attain full scratch closure after 48-hrs at concentrations below 0.3mg/mL. The seed-extracted JCEO showed significant free radical scavenging activity even at lower dilutions. It also significantly induced an anti-inflammatory effect via an increase in the release of cytokines but reduced the LPS-induced NO and TNF-α production at 0.16–0.3mg/mL. In summary, coriander essential oil demonstrated antioxidant, anti-inflammatory, and immunostimulatory effects, showcasing its therapeutic potential at specific concentrations. The findings underscore its safety and metabolic enhancement properties, emphasizing its promising role in promoting cellular health.

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The Potential Effects of the Essential Oil of Coriander Seeds on Bacterial Biofilm and Immune Cells

Cited by 2 publications

References 0 publications

Distribution of Vitamin D Status in a Group from Syrian Society

Distribution of Vitamin D Status in a Group from Syrian Society

The effect of Jordanian essential oil from coriander seeds on antioxidant, anti-inflammatory, and immunostimulatory activities using RAW 246.7 murine macrophages

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