“…The models were adjusted for age (continuous), ethnicity (White or others), education (with or without a college or university degree), Townsend deprivation index (continuous), body mass index (continuous), overall health (excellent, good, fair, or poor), hypertension (yes or no), diabetes (yes or no), sleep duration (≤ 6h, 7-8 h, or ≥ 9 h), stressful life events (yes or no), number of live births (0, 1, 2, or ≥ 3), oral contraceptive pill use (ever or never), and hormone replacement therapy use (ever or never). mediate the connection between pregnancy loss, particularly recurrent pregnancy loss, and the development of mental disorders (25). Women with a history of pregnancy loss exhibit a pro-inflammatory state (26,27), characterized by elevated levels of high-sensitivity C-reactive protein closely associated with the subsequent risk of mental disorders (28, 29).…”