The Optimum Ratio of Rocuronium and Mivacurium for Maximum Synergistic Effect

Fletcher, J.E.; Heard, Cmb

doi:10.1097/00000539-199802001-00440

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2004

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“…The group receiving 0.3 mg (1 x DE 95 ) rocuronium and 0.075 mg (1 x DE 95 ) mivacurium had a faster onset as compared to the group receiving a single rocuronium dose (0.6 mg.kg -1 ). In fact, according to Fletcher 87 , this synergism reaches its peak with the use of 1 x DE 95 of each drug. So, the association of these two neuromuscular blockers seems to be an alternative for the use of high rocuronium doses during rapid sequence induction when fast onset and short duration is desired.…”

Section: Other Techniques and New Drugsmentioning

confidence: 99%

Indução anestésica com a técnica de seqüência rápida

Moro

Módolo²

2004

Rev. Bras. Anestesiol.

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Tracheal intubation after rapid sequence induction of anesthesia is indicated for patients at risk for gastric content aspiration without suspicion of difficult intubation. The adequate indication of the technique, its judicious application and the rational use of available drugs may promote excellent intubation conditions, with fast onset, early return to consciousness and spontaneous breathing in case of tracheal intubation failure.

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Section: Other Techniques and New Drugsmentioning

confidence: 99%