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The Optic Neuritis Treatment Trial
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Cited by 58 publications
(13 citation statements)
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Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Post infectious or parainfectious optic neuritis is known to have a favourable prognosis as compared to other varieties. 3 , 9 , 17 , 18 The delayed onset and the favourable recovery both support an autoimmune process in the current case. It is imperative that we remain aware of post infectious cause of optic neuritis, which would enable a timely diagnosis and treatment.…”
Section: Discussion
supporting
confidence: 71%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Post infectious or parainfectious optic neuritis is known to have a favourable prognosis as compared to other varieties. 3 , 9 , 17 , 18 The delayed onset and the favourable recovery both support an autoimmune process in the current case. It is imperative that we remain aware of post infectious cause of optic neuritis, which would enable a timely diagnosis and treatment.…”
Section: Discussion
supporting
confidence: 71%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…[50][51][52] The current standard of care for isolated optic neuritis in humans is to avoid corticosteroid therapy as they do not improve visual recovery, and oral corticosteroids increased the risk of subsequent attacks in the affected or contralateral eye. 53 Recurrence of isolated optic neuritis in dogs has been described 23,25,28 and was noted in the current study in three cases of I-ON (2 weeks, 15 months, and 18 months after diagnosis). The small number of cases with followup in the other groups in this study did not allow for meaningful conclusions on visual prognosis.…”
Section: Discussion
supporting
confidence: 70%
“…This is in contrast to adult‐onset optic neuritis in humans, where greater than 90% of patients recover visual function spontaneously without treatment . The current standard of care for isolated optic neuritis in humans is to avoid corticosteroid therapy as they do not improve visual recovery, and oral corticosteroids increased the risk of subsequent attacks in the affected or contralateral eye . Recurrence of isolated optic neuritis in dogs has been described and was noted in the current study in three cases of I‐ON (2 weeks, 15 months, and 18 months after diagnosis).…”
Section: Discussion
mentioning
confidence: 59%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…MRI of 5 patients showed lesions suggestive of MS and already treated together with internal medicine. According to ONTT study even as many as 15 years after the initial optic neuritis attack, that the initial MRI result, if abnormal with white matter abnormalities, was the single most important predictor of the future risk of MS. 14 But the risk of MS is difficult to predict in this study because of a shorter follow-up. A Long-term study needed to know the risk of MS.…”
Section: Discussion
mentioning
confidence: 77%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Post infectious or parainfectious optic neuritis is known to have a favourable prognosis as compared to other varieties. 3 , 9 , 17 , 18 The delayed onset and the favourable recovery both support an autoimmune process in the current case. It is imperative that we remain aware of post infectious cause of optic neuritis, which would enable a timely diagnosis and treatment.…”
Section: Discussion
supporting
confidence: 71%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…[50][51][52] The current standard of care for isolated optic neuritis in humans is to avoid corticosteroid therapy as they do not improve visual recovery, and oral corticosteroids increased the risk of subsequent attacks in the affected or contralateral eye. 53 Recurrence of isolated optic neuritis in dogs has been described 23,25,28 and was noted in the current study in three cases of I-ON (2 weeks, 15 months, and 18 months after diagnosis). The small number of cases with followup in the other groups in this study did not allow for meaningful conclusions on visual prognosis.…”
Section: Discussion
supporting
confidence: 70%
“…This is in contrast to adult‐onset optic neuritis in humans, where greater than 90% of patients recover visual function spontaneously without treatment . The current standard of care for isolated optic neuritis in humans is to avoid corticosteroid therapy as they do not improve visual recovery, and oral corticosteroids increased the risk of subsequent attacks in the affected or contralateral eye . Recurrence of isolated optic neuritis in dogs has been described and was noted in the current study in three cases of I‐ON (2 weeks, 15 months, and 18 months after diagnosis).…”
Section: Discussion
mentioning
confidence: 59%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…MRI of 5 patients showed lesions suggestive of MS and already treated together with internal medicine. According to ONTT study even as many as 15 years after the initial optic neuritis attack, that the initial MRI result, if abnormal with white matter abnormalities, was the single most important predictor of the future risk of MS. 14 But the risk of MS is difficult to predict in this study because of a shorter follow-up. A Long-term study needed to know the risk of MS.…”
Section: Discussion
mentioning
confidence: 77%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…Post infectious or parainfectious optic neuritis is known to have a favourable prognosis as compared to other varieties. 3 , 9 , 17 , 18 The delayed onset and the favourable recovery both support an autoimmune process in the current case. It is imperative that we remain aware of post infectious cause of optic neuritis, which would enable a timely diagnosis and treatment.…”
Section: Discussion
supporting
confidence: 71%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…[50][51][52] The current standard of care for isolated optic neuritis in humans is to avoid corticosteroid therapy as they do not improve visual recovery, and oral corticosteroids increased the risk of subsequent attacks in the affected or contralateral eye. 53 Recurrence of isolated optic neuritis in dogs has been described 23,25,28 and was noted in the current study in three cases of I-ON (2 weeks, 15 months, and 18 months after diagnosis). The small number of cases with followup in the other groups in this study did not allow for meaningful conclusions on visual prognosis.…”
Section: Discussion
supporting
confidence: 70%
“…This is in contrast to adult‐onset optic neuritis in humans, where greater than 90% of patients recover visual function spontaneously without treatment . The current standard of care for isolated optic neuritis in humans is to avoid corticosteroid therapy as they do not improve visual recovery, and oral corticosteroids increased the risk of subsequent attacks in the affected or contralateral eye . Recurrence of isolated optic neuritis in dogs has been described and was noted in the current study in three cases of I‐ON (2 weeks, 15 months, and 18 months after diagnosis).…”
Section: Discussion
mentioning
confidence: 59%
Abstract
Smart CitationsHow this paper cites the one you are viewing
“…MRI of 5 patients showed lesions suggestive of MS and already treated together with internal medicine. According to ONTT study even as many as 15 years after the initial optic neuritis attack, that the initial MRI result, if abnormal with white matter abnormalities, was the single most important predictor of the future risk of MS. 14 But the risk of MS is difficult to predict in this study because of a shorter follow-up. A Long-term study needed to know the risk of MS.…”
Section: Discussion
mentioning
confidence: 77%