The ocular adnexa

Heathcote, J. G.

doi:10.4103/sjopt.sjopt_43_22

Cited by 5 publications

(3 citation statements)

References 17 publications

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“…Lymphomas involving the eyelids, conjunctiva, lacrimal drainage system, and orbital contents excluding the globe and optic nerve are categorized as ocular adnexal lymphomas (OAL) [ 1 ]. The most commonly involved sites are the conjunctiva and orbit whereas involvement of the lacrimal drainage system is considered rare [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

Primary ocular adnexal mantle cell lymphoma with distant spread and involvement of the contralateral eye one year later; a case report and literature review

Amir,

Sheikh

2024

Journal of Surgical Case Reports

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We herein report a middle-aged gentleman who initially presented with ocular adnexal mantle cell lymphoma (MCL) on the right eyelid. The lesion was excised and the patient was treated with radiation therapy. During the initial presentation, a PET CT was performed and did not reveal disease involvement beyond the eyelid. The patient presented 3 months later with ocular adnexal MCL of the contralateral eye. Re-evaluation using PET CT revealed a slight increase in the uptake in several lymph nodes and the spleen, which, after biopsy, confirmed systemic MCL. The patient was started on six cycles of chemotherapy. The patient also underwent autologous hematopoietic stem cell transplant. Approximately 80% of primary ocular adnexal lymphomas are B-cell in origin, with MCL being the rarest subtype constituting only 5% of B-cell ocular adnexal lymphomas. Despite its rarity, it is crucial for clinicians to detect the entity early and ensure rapid initiation of appropriate therapy.

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Section: Discussionmentioning

confidence: 99%

Primary ocular adnexal mantle cell lymphoma with distant spread and involvement of the contralateral eye one year later; a case report and literature review

Amir,

Sheikh

2024

Journal of Surgical Case Reports

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“…OALs are rare tumors involving the conjunctiva, lacrimal drainage system, eyelids, and ocular muscles [ 1 ]. Of the varying structures comprising the ocular adnexa, the orbit is most commonly involved with a reported rate of 46%–74%.…”

Section: Discussionmentioning

confidence: 99%

A case of primary conjunctival follicular lymphoma presenting as nasolacrimal obstruction

Amir,

Sheikh

2023

Journal of Surgical Case Reports

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We herein report a 76-year-old male who presented to the ophthalmology clinic after complaining from excessive lacrimation for ~6 months prior to presentation. He reports previously undergoing a nasolacrimal recanalization procedure in attempts to resolve his symptoms, but reported no improvement. On examination, a mass on the nasal conjunctiva around the medial canthus of the right eye was noted and subsequently excised. The findings support the diagnosis of low-grade follicular lymphoma. The patient was referred to radiation oncology for radiation therapy and received a total dose of 2400 cGy. Most ocular adnexal lymphomas are B-cell in origin, with follicular lymphomas being one of the rarest forms of such lymphomas. The most common translocation reported in over 85% of follicular lymphomas of the ocular adnexa is t(14; 18) (q32; q21). Traditional treatment options typically include a mix of chemical, surgical, and radio-oncological interventions.

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“…The ocular adnexa include the eyelids, conjunctival sac, lacrimal drainage system, lacrimal gland, and all orbital contents excluding the eye and optic nerve. 15 These structures undergo age-related changes that can predispose patients to developing infectious keratitis. Eyelid malposition disorders, such as entropion and ectropion, are particularly common in the aging population ( Table 1 ).…”

Section: Aging and The Ocular Adnexamentioning

confidence: 99%

Infectious Keratitis in Patients Over 65: A Review on Treatment and Preserving Eyesight

Kim,

Karslioglu,

Zhao

et al. 2024

CIA

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Infectious keratitis (IK) represents a significant global health concern, ranking as the fifth leading cause of blindness worldwide despite being largely preventable and treatable. Elderly populations are particularly susceptible due to age-related changes in immune response and corneal structure. However, research on IK in this demographic remains scarce. Age-related alterations such as increased permeability and reduced endothelial cell density further compound susceptibility to infection and hinder healing mechanisms. Additionally, inflammaging, characterized by chronic inflammation that develops with advanced age, disrupts the ocular immune balance, potentially exacerbating IK and other age-related eye diseases. Understanding these mechanisms is paramount for enhancing IK management, especially in elderly patients. This review comprehensively assesses risk factors, clinical characteristics, and management strategies for bacterial, viral, fungal, and acanthamoeba keratitis in the elderly population, offering crucial insights for effective intervention.

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The ocular adnexa

Cited by 5 publications

References 17 publications

Primary ocular adnexal mantle cell lymphoma with distant spread and involvement of the contralateral eye one year later; a case report and literature review

Primary ocular adnexal mantle cell lymphoma with distant spread and involvement of the contralateral eye one year later; a case report and literature review

A case of primary conjunctival follicular lymphoma presenting as nasolacrimal obstruction

Infectious Keratitis in Patients Over 65: A Review on Treatment and Preserving Eyesight

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