The necessity of colorectal cancer screening for elderly patients

Kudo, Shin‐ei

doi:10.21037/tgh.2017.03.03

Cited by 3 publications

(3 citation statements)

References 13 publications

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“…Since the pioneering work of Kudo, [ 16 ] multiple image‐enhanced endoscopy (IEE) techniques have aimed to reduce the number of missed lesions by increasing the contrast between normal and pathological tissue. The most widely used IEE techniques use topical dyes (chromoendoscopy), digital magnification or alternative illumination schemes to enable autofluorescence or narrow‐band imaging.…”

Section: Introductionmentioning

confidence: 99%

Robotic large‐area optical biopsy imaging for automated detection of gastrointestinal cancers tested in tissue phantoms and ex vivo porcine bowel

Avila‐Rencoret

Mylonas

Elson

2022

Transl Biophotonics

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Gastrointestinal endoscopy is a subjective procedure that frequently requires tissue samples for diagnosis. Contact optical biopsy (OB) techniques have the aim of providing direct diagnosis of endoscopic areas without excising tissue samples but lack the wide‐area coverage required for locating and resecting lesions. This article presents a large‐area robotically deployed OB imaging platform for endoscopic detection of colorectal cancer as an add‐on for conventional endoscopes. In vitro, in silicon colon phantoms, the platform achieves an optical resolution of 0.5 line pairs per millimeter, while resolving simulated cancer lesions down to 0.75 mm diameter across large‐area images (55‐103 cm2). Large‐area OB images were generated in an ex vivo porcine colon. The platform allows centimeter‐sized large‐area OB imaging in vitro and ex vivo with submillimeter resolution, including automatic data segmentation of simulated cancer areas. The ability for robotic actuation and spectrum collection is also shown for ex vivo animal colon. If successful, this technology could widen access to user‐independent high‐quality endoscopy and early detection of gastrointestinal cancers.

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Section: Introductionmentioning

confidence: 99%

Robotic large‐area optical biopsy imaging for automated detection of gastrointestinal cancers tested in tissue phantoms and ex vivo porcine bowel

Avila‐Rencoret

Mylonas

Elson

2022

Transl Biophotonics

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“…This is because: (1) healthcare access is disproportionately affected in this population (the COVID-19 case fatality rate of 9.7% in those aged ≥70 years 6 could have led to a 5-year low per capita medical expenditure specifically for those aged ≥75 years in Japan 7 ); (2) CRCS backlogs for those aged ≥70 years increased considerably during the 2020 pandemic. In the municipal-run CRCS program in Japan alone, the screening completion fell by 405,571 from 2019 to 2020 8 ; (3) delayed CRC diagnosis is more critical in them 9 ; (4) the importance of cancer prevention is still insufficiently focused in this group 10,11 (those aged >76 years are beyond the CRCS eligibility limits in most countries, despite the recommendation of up to 85 years in the United States 12 and the full eligibility in Japan); and (5) the impacts on CRC incidence (and, hence, medical expenditure) is substantial in this age group (those aged ≥70 years account for 58.9% of CRC incidence in Japan 13 ).…”

Section: Introductionmentioning

confidence: 99%

Pandemic‐resilient target setting in colorectal cancer screening for vulnerable older population

et al. 2022

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Background Colorectal cancer screening (CRCS) needs to be pandemic‐resilient to avoid long‐lasting shutdowns; however, realistic participation target remains unelucidated. This study aimed to identify the lowest acceptable participation rate in CRCS during a pandemic, focusing on vulnerable older populations who require urgent intervention. Methods This nationwide cross‐sectional study included 80,946 inpatients aged 70–85 years who were first diagnosed with colorectal cancer (CRC) after 70 years of age, between April 1, 2014 and March 31, 2019, in Japan. To evaluate the association between area‐level CRCS participation rate and individual early CRC detection, a multilevel logistic regression model was constructed. The mandatorily implemented screening rates were converted to the total screening rate equivalents (TSREs), which reflect the remaining contributions of voluntarily provided screenings. Results Early detections during stages 0–I were significantly observed when primary screening rate was ≥38% (TSRE) and combined follow‐up rate was ≥85%. For early detection during Tis–T1, primary screening rate ≥ 38% (TSRE) and combined follow‐up rate ≥ 90% were necessary. For follow‐up rates ≥70% or ≥75%, there were cases where missed detection of Tis–T1 were observed. Conclusion The results indicate that, even during pandemic, CRCS should achieve a primary screening rate of 38% and follow‐up rate of 85% for vulnerable older populations. These values, lower than the current desirable rates, suggest the maximum possible compromise in balancing the resources between cancer screening and pandemic measures. Moreover, they also indicate the minimum target for shifting to fecal immunochemical test‐focused program. Further explorations with varied CRCS settings are necessary for verification.

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“…1 With the growing geriatric population in the United States, patients are more apt to require "out of operating room" anesthesia for endoscopic procedures. 2 Variation exists on which clinicians administer sedation and/or general anesthesia for endoscopies. The clinicians vary from general practitioners, endoscopists, endoscopy-trained nurses, nurse anesthetists and anesthesiologists.…”

Section: Introductionmentioning

confidence: 99%

Airway complications during gastrointestinal endoscopies using propofol in a rural hospital

Flores

Choi

Johnson

et al. 2020

APIC

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The necessity of colorectal cancer screening for elderly patients

Cited by 3 publications

References 13 publications

Robotic large‐area optical biopsy imaging for automated detection of gastrointestinal cancers tested in tissue phantoms and ex vivo porcine bowel

Robotic large‐area optical biopsy imaging for automated detection of gastrointestinal cancers tested in tissue phantoms and ex vivo porcine bowel

Pandemic‐resilient target setting in colorectal cancer screening for vulnerable older population

Airway complications during gastrointestinal endoscopies using propofol in a rural hospital

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