Abstract:The sensor kinase/response regulator system KdpD/ KdpE of Escherichia coli regulates expression of the kdpFABC operon, which encodes the high affinity K ؉ transport system KdpFABC. The membrane-bound sensor kinase KdpD consists of an N-terminal input domain (comprising a large cytoplasmic domain and four transmembrane domains) and a cytoplasmic C-terminal transmitter domain. Here we show that the cytoplasmic N-terminal domain of KdpD (KdpD/1-395) alone supports semi-constitutive kdpFABC expression, which becom… Show more
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