The Myositis of Influenza

Mejlszenkier, Jaime D.; Safran, Arthur P.; Healy, John J.; Embree, Larry J.; Ouellette, Eileen M.

doi:10.1001/archneur.1973.00490300103017

Cited by 56 publications

(23 citation statements)

References 8 publications

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“…Of these, 28 specimens [5,8,14,17,18,23,34,36,37] had shown evidence of muscle degeneration and necrosis. Inflammatory infiltrates were found in five specimens only [5,14,18,37]. Six specimens [3,9,12,16,37] showed no or Table 1 Characteristics of five children with influenza-associated myositis (IAM).…”

Section: Discussionmentioning

confidence: 99%

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Influenza-Associated Myositis in Children

et al. 2004

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Background: Influenza-associated myositis (IAM) is an infrequent and poorly known complication of influenza virus infection in children. The aim of this study was to describe five cases of IAM and to review the literature on IAM in children. Patients and Methods:We conducted a retrospective analysis of cases of IAM diagnosed at two university children's hospitals in Switzerland during two consecutive influenza seasons. Findings were compared with 39 individual case reports and five publications summarizing an additional 272 cases identified by a medical online library (MEDLINE) search. Results: Overall, 316 cases were analyzed. IAM typically occurred in school-aged children with a 2:1 male predominance. Influenza B and A viruses were identified in 76% and 24% of cases, respectively. The median interval between onset of influenza and onset of IAM was 3 days (range 0-18). The calf muscles were involved alone or together with other muscle groups in 69% and 31% of cases, respectively. Blood creatine phosphokinase (CPK) concentration was invariably elevated. Median duration to clinical recovery was 3 days (range 1-30). Rhabdomyolysis occurred in ten of 316 patients (3%), was more common in girls (80%), more often associated with influenza A (86%), and led to renal failure in eight patients (80%). Conclusion: Clinical and laboratory findings of IAM are highly characteristic and allow a rapid diagnosis during the influenza season.

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Section: Discussionmentioning

confidence: 99%

“…The median age was 9.3 years (range [3][4][5][6][7][8][9][10][11][12][13][14]. In contrast to uncomplicated cases of IAM, which had a male predominance of 2:1 and usually affected the lower extremities, influenza-associated rhabdomyolysis occurred more often in girls (4:1), and pain and tenderness were mostly diffuse.…”

Section: Review Of the Literaturementioning

confidence: 99%

Influenza-Associated Myositis in Children

et al. 2004

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“…1971;Abramsky, 1979;Lisak et al, 1977], A viral etiology has also been sug gested in other putative autoimmune disor ders such as systemic lupus erythematosus (SLE). polymyositis, and multiple sclerosis (MS) [Hurd et al, 1972;Holtinger et al, 1971;Rowland et al, 1977;Jaime et al, 1973;Chou and Gutman. 1970;Haire.…”

Section: Discussionmentioning

confidence: 99%

Myasthenia gravis following Viral Infection

Korn¹,

Abramsky²

1981

Eur Neurol

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“…En las biopsias musculares de estos pacientes se describen desde el edema con vacuolización focal e inflamación mínima de la fibra muscular (12), hasta la necrosis muscular con reacción inflamatoria, principalmente polimorfonuclear e infiltración perivascular (13), como también cambios degenerativos inespecíficos (14). La ausencia de infiltrados inflamatorios en las biopsias musculares no excluye la existencia de una miopía de tipo inflamatorio (15).…”

Section: Discusionunclassified

Miositis aguda postinfecciosa.

Tori¹

2013

Rev Med Hered

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SUMMARYA seven year old patient in described with acute focal myositis, following an influenza-like infection, involving exclusively the gastroenemius and soleus muscles. The patient improved only with bed rest and symptomatic treatment and made a full recovery in three days. Laboratory studies showed a normal white blood count with an increase in the band forms, elevated SGOT, DHL, and CPK, all of which returned to normal after one week. The patient remains asymptomatic one month after his discharge. KEY WORDS: Acute post-infection myositis, myositis, INTRODUCCIONSe presenta un caso de miositis aguda focal transitoria, postinfecciosa, de etiología probablemente viral, en un niño de 7 años de edad, con dolor intenso en ambas pantorrillas, imposibilitándolo de mover las piernas y caminar.El objetivo de la presente comunicación es llamar la atención sobre la presencia de la asociación de miositis transitoria aguda e infecciones virales principalmente el virus de la influenza. Caso clínicoC.J.L., varón, de 7 años de edad, con antecedentes de hiperreactividad bronquial. Cuatro días antes de su ingreso había estado medicado con dicloxacilina y acetaminofén por un cuadro infeccioso respiratorio alto, caracterizado por fiebre, malestar general, coriza y tos. Siete horas antes de hospitalizarse, despierta con dolor intenso en ambas pantorrillas que le impedía mantenerse de pie y caminar El paciente estaba febril pero en buen estado general, con tos irritativa y con un dolor exquisito en ambas pantorrillas, tanto espontáneo como a la palpación. El tímpano derecho estaba congestivo. La faringe presentaba congestión sin exudados. Al examen pulmonar se encontró sibilantes y roncantes escasos en campos pulmonares. El abdomen era blando,

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The Myositis of Influenza

Cited by 56 publications

References 8 publications

Influenza-Associated Myositis in Children

Influenza-Associated Myositis in Children

Myasthenia gravis following Viral Infection

Miositis aguda postinfecciosa.

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