volume 25, issue 1, P47-50 2011
DOI: 10.3233/jad-2011-101983
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Reposo Ramírez-Lorca, Mercé Boada, Carmen Antúnez, Jesús López-Arrieta, Concha Moreno-Rey, Isabel Hernández, Juan Marín, Javier Gayán, Antonio González-Pérez, Montserrat Alegret, Lluis Tárraga, Luis M. Real, Agustín Ruiz

Abstract: The MTHFD1L gene SNP variant rs11754661 was found to increase the risk of Alzheimer's disease in a recent Whole Genome Association Study. We have carried out an independent study of this genetic variant in 2467 individuals from Spain. We found no evidence of association between the MTHFD1L marker and susceptibility to Alzheimer's disease in our sample.