The modulation by metallothionein of cadmium-induced cytotoxicity in primary hepatocyte cultures

Cadmium uptake in rat hepatocytes in relation to speciation and to complexation with metallothionein and albumin

“…3) from Cd 7 MT would be about 0.4 times as rapidly as Cd inorg , for non-saturating initial rate conditions. This difference in uptake efficiency may explain the reported lower toxicity of Cd-MT compared to CdCl 2 in rat hepatocytes (Beattie et al, 1987;Sendelbach et al, 1989).…”

Cadmium uptake in rat hepatocytes in relation to speciation and to complexation with metallothionein and albumin

“…3) from Cd 7 MT would be about 0.4 times as rapidly as Cd inorg , for non-saturating initial rate conditions. This difference in uptake efficiency may explain the reported lower toxicity of Cd-MT compared to CdCl 2 in rat hepatocytes (Beattie et al, 1987;Sendelbach et al, 1989).…”

Cadmium uptake in rat hepatocytes in relation to speciation and to complexation with metallothionein and albumin

“…3) from Cd 7 MT would be about 0.4 times as rapidly as Cd inorg , for non-saturating initial rate conditions. This difference in uptake efficiency may explain the reported lower toxicity of Cd-MT compared to CdCl 2 in rat hepatocytes (Beattie et al, 1987;Sendelbach et al, 1989).…”

Cadmium uptake in rat hepatocytes in relation to speciation and to complexation with metallothionein and albumin

“…3) from Cd 7 MT would be about 0.4 times as rapidly as Cd inorg , for non-saturating initial rate conditions. This difference in uptake efficiency may explain the reported lower toxicity of Cd-MT compared to CdCl 2 in rat hepatocytes (Beattie et al, 1987;Sendelbach et al, 1989).…”