The Microbiology of Recurrent Rhinosinusitis After Endoscopic Sinus Surgery

Abstract

A wide range of bacteria may be present in the infected post-ESS sinus cavity, with a considerable population of gram-negative organisms, including Pseudomonas species. Beta-Lactamase-producing organisms continue to be prevalent in postoperative sinus infections. Culture and sensitivity analyses of pathologic secretions may identify drug-resistant organisms or organisms related to difficult-to-treat infections in exacerbations of chronic rhinosinusitis in the postoperative setting.

The incidence of anaerobic bacteria in adult patients with chronic sinusitis: A prospective, single-centre microbiological study

“…could be attributed to the applied longer incubation period (6-8 days) [42]. The distribution of aerobic and/or facultative anaerobic pathogens in the present investigation was consistent with that seen in some of the other studies of chronic sinusitis [21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36]. Similar to the data available in the literature, S. pneumoniae (50.6%), H. influenzae (36.7%) and M. catarrhalis (7.6%) were among the most frequently isolated aerobic and/or facultative anaerobic pathogens.…”

Microbiological Profiles and Patterns of Resistance in Patients With Sinus Infections After Endoscopic Sinus Surgery

“…We report an even greater Gram‐negative predominance, which may indicate a shift toward more Gram‐negative infections post‐ESS in our region and/or an increase in their pathogenicity. The individual Gram‐negative organisms are also similar to previous reports, with our proportion of Enterobacteriaceae (17.7%) and P. aeruginosa (8.5%) 6,17,20 . P. aeruginosa (and S. aureus) have both been highlighted in CRS for their biofilm‐producing abilities, leading to poorer quality of life and clinical outcomes post‐ESS 23,24 .…”

Endoscopic culture-directed antibiotic therapy: Impact on patient symptoms in chronic rhinosinusitis

“…The disparity between the available evidence base and existing clinical practice served as an important impetus for the current series. The preponderance of S. aureus and P. aeruginosa in this series has been observed in previous series [5,10]. Cincik and Ferguson noted prevalence of S. aureus and P. aeruginosa in 33% and 18.5% of patients presenting with acute exacerbation of CRS [5].…”