The metabolomic profile of Garcinia intermedia leaves with several sample drying methods

Abstract

Garcinia intermedia, commonly called cherry mangosteen or lemon drop mangosteen, originates from Mexico and Central America. This plant is not cultivated in Indonesia because the fruit is less tasty than mangosteen (Garcinia mangostana). Information about the metabolome content in Garcinia intermedia needs to be known to increase its commercial use. Several studies have shown that this species has anti-microbial content that benefits health. This study aims to perform metabolomics profiling in the leaves of Garcinia intermedia using 3 (three) treatments of leaves drying methods such as air-dried (room temperature), freeze-drying, and oven (hot air) through Gas Chromatography-Mass Spectrophotometry (GC-MS). The results identified a total of 35 different compounds in the leaves of Garcinia intermedia. The highest area pct was Friedelan-3-one (29.92%) obtained from air-dried preparation method. The other identified compounds were the sesquiterpenes group (beta-Caryophyllene, gamma-Muurolene, Naphthalene,1,2,3,5,6,8a-hexahydro-4,7-dimethyl-1- (1-methylethyl)-,(1S-cis)-, and 1-Isopropyl-4,7-dimethyl-1,2,3,5,6,8a-hexahydronaphthalene), Alkane group (Octadecane and Heptacosane) and vitamin E (delta-Tocopherol and dl-alpha-Tocopherol). This study revealed the insight of potential uses of Garcinia intermedia leaves extract with additional functional metabolites that could further be used to discover potential drugs that benefits for human health.