The meiotic behaviour of the XY pair in Lutreolina crassicaudata (Marsupialia: Didelphoidea)

Roche, L.; Seluja, Gustavo A.; Wettstein, R.

doi:10.1007/bf00057694

Cited by 12 publications

(15 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…. The location of AE and CA proteins on the sex chromosomes in male marsupials is consistent with this deviates from that of most eutherian species (Solari and Bianchi 1975;Sharp 1982;Roche et al 1986; Seluja model. Therefore, AEs and CAs should be considered as different structures, and more significantly, they could be et al.…”

Section: Specific Phosphorylation Of Sex Chromosomal Aessupporting

confidence: 70%

“…We found that SCP3 and the cohesin subunits STAG3 and SMC3 recruitment of components of the CE of the SC and A series of morphological and genetic studies have revealed that the orders Didelphimorphia and Paucituberculata to which T. elegans and R. raphanurus, respectively, belong, are the most basal groups within marsupials (Szalay 1994;Amrine-Madsen et al 2003;Nilsson et al 2003). As for D. gliroides, it has been repeatedly claimed that, in spite of its South American distribution, this species is more closely related to Australian marsupials (Kirsch et al 1991;Szalay 1994;Spotorno et al 1997;Palma and Spotorno 1999;Janke et al 2002;Amrine-Madsen et al 2003;Nilsson et al 2003). Taken together, such relationships give support to the idea that the special features that sex chromosomes present during meiosis could have originated very early in the evolution of marsupials [stemming at least from the radiation of the extant marsupial orders 64 million years ago (Nilsson et al 2003)], and they would have been line in some marsupial species (Hayman 1990;Palma 1995), including D. gliroides (Gallardo and Paterson 1987).…”

Section: Specific Phosphorylation Of Sex Chromosomal Aesmentioning

confidence: 99%

“…Instead, and/or selective forces (Maynard Smith and Haigh a specific structure called dense plate (DP) appears 1974; Charlesworth 1991; Rice 1996; Bachtrog associating the ends of sex chromosomal AEs (Solari 2004). andBianchi 1975;Sharp 1982;Roche et al 1986; Seluja The genetic differentiation of sex chromosomes poses et al 1987). The DP maintains sex chromosome associaa serious problem for these chromosomes to perform a tion at least up to the end of the pachytene stage of the proper meiotic behavior.…”

mentioning

confidence: 99%

See 2 more Smart Citations

The Program of Sex Chromosome Pairing in Meiosis Is Highly Conserved Across Marsupial Species

et al. 2005

View full text Add to dashboard Cite

Marsupials present a series of genetic and chromosomal features that are highly conserved in very distant species. One of these features is the absence of a homologous region between X and Y chromosomes. According to this genetic differentiation, sex chromosomes do not synapse during the first meiotic prophase in males, and a special structure, the dense plate, maintains sex chromosome association. In this report we present results on the process of meiotic sex chromosome pairing obtained from three different species, Thylamys elegans, Dromiciops gliroides, and Rhyncholestes raphanurus, representing the three orders of American marsupials. We have investigated the relationships between the axial structures organized along sex chromosomes and the formation of the dense plate. We found that in the three species the dense plate arises as a modification of sex chromosomal axial elements, but without the involvement of other meiotic axial structures, such as the cohesin axes. Considering the phylogenetic relationships among the marsupials studied here, our data reinforce the idea that the dense plate emerged early in marsupial evolution as an efficient mechanism to ensure the association of the nonhomologous sex chromosomes. This situation could have influenced the further evolution of sex chromosomes in marsupials.

show abstract

Section: Specific Phosphorylation Of Sex Chromosomal Aessupporting

confidence: 70%

Section: Specific Phosphorylation Of Sex Chromosomal Aesmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

The Program of Sex Chromosome Pairing in Meiosis Is Highly Conserved Across Marsupial Species

et al. 2005

View full text Add to dashboard Cite

show abstract

“…In most marsupial species, sex chromosomes do not possess a PAR and sex chromosomes do not synapse at all. Instead, they develop a specific structure, called dense plate, which maintains their association (Solari and Bianchi 1975;Sharp 1982;Roche et al 1986;Seluja et al 1987). This structure is formed by the modification of sex chromosomal AEs, which expand on the nuclear envelope giving rise to a dishlike structure in which the ends of the X and Y AEs are immersed (Fig.…”

Section: Marsupial Sex Chromosomal Aes Expand At Their Ends To Form Amentioning

confidence: 99%

Sex chromosomes, synapsis, and cohesins: a complex affair

et al. 2006

View full text Add to dashboard Cite

During first meiotic prophase, homologous chromosomes are held together by the synaptonemal complex, a tripartite proteinaceous structure that extends along the entire length of meiotic bivalents. While this feature is applicable for autosomes, sex chromosomes often escape from this rule. Many species present sex chromosomes that differ between them in their morphology, length, and gene content. Moreover, in some species, sex chromosomes appear in a single dose in one of the sexes. In all of these cases, the behavior of sex chromosomes during meiosis is conspicuously affected, and this includes the assembly and dynamics of the synaptonemal complex. We review in this study the structure of the synaptonemal complex in the sex chromosomes of three groups of organisms, namely: mammals, orthopterans, and hemipterans, which present different patterns of sex chromosome structure and behavior. Of special interest is the analysis of the organization of the axial/lateral elements of the synaptonemal complex in relation to other axial structures organized along meiotic chromosomes, mainly the cohesin axis. The differences found in the behavior of both axial structures reveal that while the organization of a cohesin axis along sex chromosomes is a conserved feature in most organisms and it shows very little morphological variations, the axial/lateral elements of the synaptonemal complex present a wide range of structural modifications on these chromosomes.

show abstract

“…However, little attention has been paid to the meiotic structure and behaviour of sex chromosomes in the other mammalian taxa, the monotremes and the marsupials. There is only one report on monotreme meiosis (Murtagh, 1977), whereas the meiosis of only some American and Australian marsupial species has been thoroughly described (Koller, 1936;Solari and Bianchi, 1975;Pathak et al, 1980;Sharp, 1982;Roche et al, 1986;Seluja et al, 1987). Some of the features found in eutherian males are also observed in marsupial males.…”

Section: Introductionmentioning

confidence: 99%

The pairing of X and Y chromosomes during meiotic prophase in the marsupial species Thylamys elegans is maintained by a dense plate developed from their axial elements

Page

Berríos

Rufas

et al. 2003

Journal of Cell Science

View full text Add to dashboard Cite

Unlike eutherian males, pairing of the sex chromosomes in marsupial males during the first meiotic prophase is not mediated by a synaptonemal complex. Instead, a specific structure, the dense plate, develops during pachytene between the sex chromosomes. We have investigated the development and structural nature of this asynaptic association in males of the marsupial species Thylamys elegans by means of immunolabelling and electron microscopy techniques. Our results show that the behaviour of male marsupial sex chromosomes during first meiotic prophase is complex, involving modifications of their structure and/or composition. Pairing of the sex chromosomes and formation of the dense plate take place in mid pachytene,paralleling morphological changes in the sex chromosomal axial elements. Components of the central element of the synaptonemal complex were not found in the sex body, in agreement with ultrastructural studies that reported the absence of a canonical tripartite synaptonemal complex between male marsupial sex chromosomes. Interestingly, the dense plate is labelled with antibodies against the SCP3 protein of the lateral elements of the synaptonemal complex. Moreover, as sex chromosome axial elements decrease in mass throughout mid-late pachytene, the dense plate increases, suggesting that material moves from the axial elements to the dense plate. Additionally, both sex chromosome axial elements and the dense plate have proteins that are specifically phosphorylated, as revealed by their labelling with the MPM-2 antibody,indicating that they undergo a chromosome-specific regulation process throughout first meiotic prophase. We propose that the unique modifications of the composition and structure of the axial elements of the sex chromosomes in meiotic prophase may result in the proscription of synaptonemal complex formation between male marsupial sex chromosomes, where the dense plate is an extension of the axial elements of sex chromosomes. This replaces synapsis to maintain X and Y association during first meiotic prophase.

show abstract

The meiotic behaviour of the XY pair in Lutreolina crassicaudata (Marsupialia: Didelphoidea)

Cited by 12 publications

References 31 publications

The Program of Sex Chromosome Pairing in Meiosis Is Highly Conserved Across Marsupial Species

The Program of Sex Chromosome Pairing in Meiosis Is Highly Conserved Across Marsupial Species

Sex chromosomes, synapsis, and cohesins: a complex affair

The pairing of X and Y chromosomes during meiotic prophase in the marsupial species Thylamys elegans is maintained by a dense plate developed from their axial elements

Contact Info

Product

Resources

About