The marine Gram-negative bacterium Novosphingobium sp. PP1Y as a potential source of novel metabolites with antioxidant activity

Petruk, Ganna; Roxo, Mariana; Lise, Federica De; Mensitieri, Francesca; Notomista, Eugenio; Izzo, Viviana; Monti, Daria Maria

doi:10.1007/s10529-018-02636-4

Cited by 12 publications

(6 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The DPPH assay is useful for investigating the antioxidant properties of extracts obtained using various solvents, is cheap and easy to implement, and can be applied to both hydrophilic and lipophilic antioxidants [ 18 ]. In addition, this assay has been successfully used to measure the antioxidant activities of carotenoids, polysaccharides, and MeOH extracts of marine microorganisms [ 24 , 25 , 26 ]. Therefore, this method can be chosen as an effective method for comprehensively screening the antioxidant effects of supernatant containing various substances.…”

Section: Discussionmentioning

confidence: 99%

Optimising the DPPH Assay for Cell-Free Marine Microorganism Supernatants

et al. 2021

View full text Add to dashboard Cite

Antioxidants prevent ageing and are usually quantified and screened using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. However, this assay cannot be used for salt-containing samples, such as the cell-free supernatants of marine microorganisms that are aggregated under these conditions. Herein, the DPPH solvent (methanol or ethanol) and its water content were optimized to enable the analysis of salt-containing samples, aggregation was observed for alcohol contents of >70%. The water content of methanol influenced the activities of standard antioxidants but did not significantly affect that of the samples. Based on solution stability considerations, 70% aqueous methanol was chosen as the optimal DPPH solvent. The developed method was successfully applied to the cell-free supernatants of marine bacteria (Pseudoalteromonas rubra and Pseudoalteromonas xiamenensis), revealing their high antioxidant activities. Furthermore, it was concluded that this method would be useful for the screening of marine microorganism–derived antioxidants, which also has numerous potential applications, such as salt-fermented foods.

show abstract

Section: Discussionmentioning

confidence: 99%

Optimising the DPPH Assay for Cell-Free Marine Microorganism Supernatants

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The EC50 of Fw-1 on the scavenging of hydroxyl and superoxide radicals was 1.1 and 2.0 mg/mL, respectively, which was larger than that of the EPS named as AVP isolated from the marine Aspergillus Versicolor LCJ-5-4 (EC 50 is 4.0 mg/mL). The antioxidant EPS extracted from marine fungi had a relatively simple monosaccharide composition and a small molecular weight, which was more suitable for studying the relationship between the structure of the marine polysaccharides and antioxidants [ 80 , 120 ].…”

Section: The Biological Activities Of Marine Epsmentioning

confidence: 99%

Exopolysaccharides from Marine Microbes: Source, Structure and Application

Zheng

et al. 2022

Marine Drugs

View full text Add to dashboard Cite

The unique living environment of marine microorganisms endows them with the potential to produce novel chemical compounds with various biological activities. Among them, the exopolysaccharides produced by marine microbes are an important factor for them to survive in these extreme environments. Up to now, exopolysaccharides from marine microbes, especially from extremophiles, have attracted more and more attention due to their structural complexity, biodegradability, biological activities, and biocompatibility. With the development of culture and separation methods, an increasing number of novel exopolysaccharides are being found and investigated. Here, the source, structure and biological activities of exopolysaccharides, as well as their potential applications in environmental restoration fields of the last decade are summarized, indicating the commercial potential of these versatile EPS in different areas, such as food, cosmetic, and biomedical industries, and also in environmental remediation.

show abstract

“…Keeping the capacity of bio-pigments into consideration, many biotech industries are now developing protocols for efficient extraction of natural pigments as a replacement to synthetic counterparts. For instance, natural pigments such as zeaxanthin, saproxanthin, myxol and many others which illicit antioxidant activities are being instigated against artificial antioxidants such as butylated hydroxyl toluene and butylated hydroxyl acids [12,13].…”

Section: Bacterial Pigments As Natural Colorantsmentioning

confidence: 99%

An Overview on Industrial and Medical Applications of Bio-Pigments Synthesized by Marine Bacteria

et al. 2020

View full text Add to dashboard Cite

Marine bacterial species contribute to a significant part of the oceanic population, which substantially produces biologically effectual moieties having various medical and industrial applications. The use of marine-derived bacterial pigments displays a snowballing effect in recent times, being natural, environmentally safe, and health beneficial compounds. Although isolating marine bacteria is a strenuous task, these are still a compelling subject for researchers, due to their promising avenues for numerous applications. Marine-derived bacterial pigments serve as valuable products in the food, pharmaceutical, textile, and cosmetic industries due to their beneficial attributes, including anticancer, antimicrobial, antioxidant, and cytotoxic activities. Biodegradability and higher environmental compatibility further strengthen the use of marine bio-pigments over artificially acquired colored molecules. Besides that, hazardous effects associated with the consumption of synthetic colors further substantiated the use of marine dyes as color additives in industries as well. This review sheds light on marine bacterial sources of pigmented compounds along with their industrial applicability and therapeutic insights based on the data available in the literature. It also encompasses the need for introducing bacterial bio-pigments in global pigment industry, highlighting their future potential, aiming to contribute to the worldwide economy.

show abstract

The marine Gram-negative bacterium Novosphingobium sp. PP1Y as a potential source of novel metabolites with antioxidant activity

Cited by 12 publications

References 24 publications

Optimising the DPPH Assay for Cell-Free Marine Microorganism Supernatants

Optimising the DPPH Assay for Cell-Free Marine Microorganism Supernatants

Exopolysaccharides from Marine Microbes: Source, Structure and Application

An Overview on Industrial and Medical Applications of Bio-Pigments Synthesized by Marine Bacteria

Contact Info

Product

Resources

About