The Lymphatic Vessels of the Thyroid Gland in the Dog and in Man

Vascular Patterns in Tissues and Grafts Within Transparent Chambers in Mice

“…No evidence was found for the presence of A-V anastomoses. These observations are in contradiction to frequent statements in the literature that each follicle has its own individual arteriole, venule, and capillary network (13,14). These observations are of importance for the development of a thyroid model, which would describe exchange of iodide between blood and thyroid gland (15).…”

Clonal analysis of bilateral, recurrent, and metastatic papillary thyroid carcinomas

“…In this view, such alterations can be used as a valid marker for clonality analysis. During further development, daughters of this transformed cell could gradually migrate regionally through an abundant network of intralobar lymphatic vessels [34]. These vessels, which intercommunicate from lobe to lobe across the isthmus, would allow tumor metastases ready access to the contralateral lobe.…”

Lymphatic Vessel Network Structure and Physiology

“…Lymphatic vessels can also be found within the interlobular spaces passing between groups of follicles. Unlike capillary networks, the lymphatic capillaries generally do not come into direct contact with the follicles (745, 795, 909). The thyroid lymphatics have been labeled positive for Lyve1, Prox1, and podoplanin in the mouse (358) and for Lyve1 in the rat (795).…”

“…The thyroid gland plays an important role in growth and development. A plexus of anastomosing lymphatic vessels has been described as enshrouding the thyroid glands of dogs and cats, and to a lesser extent in rabbits and monkeys (232, 825, 909). Lymphatic vessels can also be found within the interlobular spaces passing between groups of follicles.…”