The long‐term prognosis in untreated cerebral aneurysms: I. The incidence of late hemorrhage in cerebral aneurysm: A 10‐year evaluation of 364 patients

Abstract

Three hundred sixty-four patients who suffered a subarachnoid hemorrhage from an aneurysm in either the posterior communicating or anterior communicating artery and who were not surgically treated have been followed for up to 21 years in order to determine the frequency of subsequent hemorrhage. For patients surviving six months: (1) rebleeding occurs on the average of 3.5% per year during the first decade; (2) the mortality associated with a late rebleed is 67%; (3) high blood pressure and female sex predispose to late rebleeding in posterior communicating artery aneurysms; (4) young patients take longer to rebleed than older patients but do so at the same rate; and (5) increase in aneurysm size as judged by routine arteriography six months after the initial hemorrhage did not correlate with rebleeding, although an increase in size had occurred in all patients who were studied angiographically at the time of their late rebleed.

Outcome of microsurgical clipping of ruptured intracranial aneurysms: An early experience

“…The incidence of aneurysm rupture is highest during fifth and sixth decade of life and gradually increases with each decade and more common in females. 12 In our series majority of the patients were between 50-65 years of age with female predominance which is comparable with other international literatures. 13 More than half of the patients in our study presented with rupture of MCA bifurcation aneurysm which is different from various other studies which shows Anterior communicating artery aneurysms as the most common (35%) followed by MCA bifurcation (22%).…”

Outcome of microsurgical clipping of ruptured intracranial aneurysms: An early experience

“…The incidence of aneurysm rupture is highest during fifth and sixth decade of life and gradually increases with each decade and more common in females. 12 In our series majority of the patients were between 50-65 years of age with female predominance which is comparable with other international literatures. 13 More than half of the patients in our study presented with rupture of MCA bifurcation aneurysm which is different from various other studies which shows Anterior communicating artery aneurysms as the most common (35%) followed by MCA bifurcation (22%).…”

Outcome of Microsurgical Clipping of Intracranial Aneurysms in Bir Hospital

“…There were 48(38%) male and 79(62%) female in this retrospective study and these findings are similar to literatures that cerebral aneurysms are more common in female than male 30,31 , however, reason behind this is not known.…”

“…The incidence of aneurismal rupture is gradually increases for each decade and peaks in 6 th decade. 30,31 Our series also shows the similar result that majority of patients belonged to 40-70 age groups.…”

Coating of intracranial aneurysms: A long-term follow-up study of 34 cases

“…The early rebleeding rate was relatively high (4 cases within 32 days, 12%), a finding also reported by others [2,26]. Our late rebleeding rate of 0.7% per year is lower than the 3 to 4% per year for untreated ruptured aneurysms [27] and more comparable to the natural history of unruptured aneurysms [12]. Noteworthy is the high mortality of rebleeding: in our patients, all recurrent haemorrhages were fatal.…”

Outcome of microsurgical clipping of ruptured intracranial aneurysms: An early experience

“…The incidence of aneurysm rupture is highest during fifth and sixth decade of life and gradually increases with each decade and more common in females. 12 In our series majority of the patients were between 50-65 years of age with female predominance which is comparable with other international literatures. 13 More than half of the patients in our study presented with rupture of MCA bifurcation aneurysm which is different from various other studies which shows Anterior communicating artery aneurysms as the most common (35%) followed by MCA bifurcation (22%).…”

Outcome of Microsurgical Clipping of Intracranial Aneurysms in Bir Hospital

“…There were 48(38%) male and 79(62%) female in this retrospective study and these findings are similar to literatures that cerebral aneurysms are more common in female than male 30,31 , however, reason behind this is not known.…”

“…The incidence of aneurismal rupture is gradually increases for each decade and peaks in 6 th decade. 30,31 Our series also shows the similar result that majority of patients belonged to 40-70 age groups.…”

Coating of intracranial aneurysms: A long-term follow-up study of 34 cases

“…The early rebleeding rate was relatively high (4 cases within 32 days, 12%), a finding also reported by others [2,26]. Our late rebleeding rate of 0.7% per year is lower than the 3 to 4% per year for untreated ruptured aneurysms [27] and more comparable to the natural history of unruptured aneurysms [12]. Noteworthy is the high mortality of rebleeding: in our patients, all recurrent haemorrhages were fatal.…”

Outcome of microsurgical clipping of ruptured intracranial aneurysms: An early experience

“…The incidence of aneurysm rupture is highest during fifth and sixth decade of life and gradually increases with each decade and more common in females. 12 In our series majority of the patients were between 50-65 years of age with female predominance which is comparable with other international literatures. 13 More than half of the patients in our study presented with rupture of MCA bifurcation aneurysm which is different from various other studies which shows Anterior communicating artery aneurysms as the most common (35%) followed by MCA bifurcation (22%).…”

Outcome of Microsurgical Clipping of Intracranial Aneurysms in Bir Hospital

“…There were 48(38%) male and 79(62%) female in this retrospective study and these findings are similar to literatures that cerebral aneurysms are more common in female than male 30,31 , however, reason behind this is not known.…”

“…The incidence of aneurismal rupture is gradually increases for each decade and peaks in 6 th decade. 30,31 Our series also shows the similar result that majority of patients belonged to 40-70 age groups.…”

Coating of intracranial aneurysms: A long-term follow-up study of 34 cases

“…The early rebleeding rate was relatively high (4 cases within 32 days, 12%), a finding also reported by others [2,26]. Our late rebleeding rate of 0.7% per year is lower than the 3 to 4% per year for untreated ruptured aneurysms [27] and more comparable to the natural history of unruptured aneurysms [12]. Noteworthy is the high mortality of rebleeding: in our patients, all recurrent haemorrhages were fatal.…”