The long non-coding RNA ZFAS1 promotes colorectal cancer progression via miR200b/ZEB1 axis

Salman, Isam Noori; Abulsoud, Ahmed I.; Abo-Elmatty, Dina M.; Fawzy, Amal; Mesbah, Noha M.; Saleh, Samy M.

doi:10.1016/j.prp.2023.154567

Cited by 27 publications

(1 citation statement)

References 42 publications

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“…Several complicated disorders have been linked to the improper regulation of non-coding RNAs. It is possible to affect cell function if the processing of these small but powerful regulators is disrupted ( Abd El Fattah et al, 2023 ; El-Sheikh et al, 2023 ; Salman et al, 2023 ).…”

Section: Mirnas Biogenic Pathways and Functionmentioning

confidence: 99%

Decoding the secrets of longevity: unraveling nutraceutical and miRNA-Mediated aging pathways and therapeutic strategies

Salama,

Eissa,

Doghish

et al. 2024

Front. Aging

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MicroRNAs (miRNAs) are short RNA molecules that are not involved in coding for proteins. They have a significant function in regulating gene expression after the process of transcription. Their participation in several biological processes has rendered them appealing subjects for investigating age-related disorders. Increasing data indicates that miRNAs can be influenced by dietary variables, such as macronutrients, micronutrients, trace minerals, and nutraceuticals. This review examines the influence of dietary factors and nutraceuticals on the regulation of miRNA in relation to the process of aging. We examine the present comprehension of miRNA disruption in age-related illnesses and emphasize the possibility of dietary manipulation as a means of prevention or treatment. Consolidating animal and human research is essential to validate the significance of dietary miRNA control in living organisms, despite the abundance of information already provided by several studies. This review elucidates the complex interaction among miRNAs, nutrition, and aging, offering valuable insights into promising areas for further research and potential therapies for age-related disorders.

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Section: Mirnas Biogenic Pathways and Functionmentioning

confidence: 99%