The Lipids of Serum and Liver in Patients With Hepatic Diseases 1

The effect of feeding cholesterol without fat on the plasma-lipids of the rabbit. The role of cholesterol in fat metabolism

“…In fig. 9 the log of serum free cholesterol (x') is plotted against the log of serum lipoid phosphorus (p') as calculated from the values found by Man, Kartin, Durlacher & Peters (1945) in patients with various forms of liver disease. It can be seen that there is a good approximation to linearity although there is a greater scattering of the points than in Fig.…”

“…serum lipid phosphorus (p') in cases of liver diseases in human patients. Log values calculated from data of Man et al (1945 (1942,1944,1945) 2. Amorphous cholesterol fed in a watery suspension is well absorbed by rabbits and causes a rise in the free and esterified cholesterol, phospholipids and neutral fats of the plasma 24 hr.…”

Characterization of components of inhibitory-factor (troponin B) preparations of the myofibril

“…Disturbances in lipid metabolism have been reported in human and experimental obstructive jaundice. Thus human studies have shown elevated concentrations of plasma free fatty acids (Mortiaux & Dawson, 1961), serum triglycerides (Mendenhall & Mortiaux, 1961) and cholesterol (Man, Kartin, Durlacher & Peters, 1945), whereas in animal experiments elevated concentrations of cholesterol (Byers, Freedman & Michaelis, 1951) and abolition of the negative-feedback regulation of cholesterol biosynthesis (Katterman & Creutzfeldt, 1970) have been described. The purpose of the present investigation was to study lipid and ketone-body metabolism in the rat during experimental cholestasis.…”

Serum Iodine in Hypothyroidism Before and During Thyroid Therapy 12

“…4774, B55424, B56968, and 73340), 3 were suffering from severe malnutrition, 1 died soon afterwards with advanced hepatic insufficiency, 1 had active pulmonary tuberculosis, and 1 was without obvious complications. Both malnutrition and advanced hepatic insufficiency are known to be associated with depression of the serum cholesterol (23,24,25). Hypercholesterolemia is not, therefore, an obligatory accompaniment of hypothyroidism, and, in the presence of nutritional deficiency or advanced liver disease, the serum cholesterol level may be normal or even exceedingly low (73340).…”