The late prognosis of perforated duodenal ulcer

Dean, A. C. B.; Clark, C. G.; Sinclair-Gieben, A. H. C.

doi:10.1136/gut.3.1.60

Cited by 22 publications

(6 citation statements)

References 9 publications

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“…Surgical management, which included bowel resection and anastomosis, stoma creation, and closure of perforations, was dependent on the intraoperative findings and to the surgeon's judgment, and the options adopted were similar to those reported in other studies. 1,7,10 The rate of mortality found in our study (22.2%), was comparable to results found in other studies in Africa, as it was found to be 20% in studies done in Nigeria. 10,11 Contrary to results of other studies done in children, 10,11 younger age was not associated with mortality in our sample.…”

Section: Discussionsupporting

confidence: 90%

Epidemiological study of peritonitis among children and factors predicting mortality at a tertiary referral hospital in Rwanda

Mutabazi¹,

Bonane²,

Ndibanje³

et al. 2018

East. Cent. Afr. J. Surg.

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Background: Peritonitis is a commonly encountered paediatric surgical emergency. We conducted this study to identify common causes of peritonitis among Rwandan children and factors affecting morbidity and mortality. Methods: The study sample consisted of children with peritonitis who underwent surgical treatment at a tertiary referral hospital in Rwanda from 1 September 2015 to 28 February 2016. Collected data included sociodemographic, clinical, paraclinical, management, and outcome information. The analysis included Pearson's chi-square test and multivariate logistic regression to determine factors associated with morbidity and mortality.Results : Of 63 patients, 28 were female. Ages ranged from 4 months to 15 years, with a mean of 8.8 years. Seventy-three percent of patients presented within the first week of symptom onset. Appendicular perforation (25.4%) and gangrenous intussusception (23.8%) were the most common causes of peritonitis. = 7.38; 95% CI = 1.20 to 45.3; P = 0.031). Fourteen patients (22.2%) died. On multivariate analysis, factors associated with mortality included sepsis (odds ratio [OR] = 11.60; 95% confidence interval [CI] = 2.15 to 62.5; P = 0.004) and intensive care unit (ICU) admission (OR Conclusions: Peritonitis among children is common and bears significant morbidity and mortality at our centre. Training of healthcare providers in district hospitals for early recognition of peritonitis, and improved ICU care availability may reduce mortality secondary to peritonitis in children.

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Section: Discussionsupporting

confidence: 90%

Epidemiological study of peritonitis among children and factors predicting mortality at a tertiary referral hospital in Rwanda

Mutabazi¹,

Bonane²,

Ndibanje³

et al. 2018

East. Cent. Afr. J. Surg.

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“…8,10 More commonly the perforations involved the proximal part of gastrointestinal tract. 6,[11][12][13] 8,14,15 Our observations are also in contrast to studies from western countries where perforations were more common in the distal part. 16,17 It may be noted that then spectrum of perforation peritonitis in India continues to be different from western counterparts.…”

Section: Discussionmentioning

confidence: 62%

A retrospective study of perforation peritonitis in a tertiary care hospital in Uttar Pradesh, India

et al. 2016

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“…More commonly the perforations involve the proximal part of the gastrointestinal tract; [ 10 – 13 ] this being in contrast to studies from the western countries, where perforations are common in the distal part [ 14 – 16 ].…”

Section: Discussionmentioning

confidence: 99%

Perforation Peritonitis and the Developing World

et al. 2014

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Background. Perforation peritonitis is the one of the commonest emergency encountered by surgeons. The aim of this paper is to provide an overview of the spectrum of perforation peritonitis managed in a single unit of a tertiary care hospital in Delhi. Methods. A retrospective study was carried out between May 2010 and June 2013 in a single unit of the department of Surgery, Lok Nayak Hospital, Delhi. It included 400 patients of perforation peritonitis (diffuse or localized) who were studied retrospectively in terms of cause, site of perforation, surgical treatment, complications, and mortality. Only those patients who underwent exploratory laparotomy for management of perforation peritonitis were included. Results. The commonest cause of perforation peritonitis included 179 cases of peptic ulcer disease (150 duodenal ulcers and 29 gastric ulcers) followed by appendicitis (74 cases), typhoid fever (48 cases), tuberculosis (40 cases), and trauma (31). The overall mortality was 7%. Conclusions. Perforation peritonitis in India has a different spectrum as compared to the western countries. Peptic ulcer perforation, perforating appendicitis, typhoid, and tubercular perforations are the major causes of gastrointestinal perforations. Early surgical intervention under the cover of broad spectrum antibiotics preceded by adequate aggressive resuscitation and correction of electrolyte imbalances is imperative for good outcomes minimizing morbidity and mortality.

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The late prognosis of perforated duodenal ulcer

Cited by 22 publications

References 9 publications

Epidemiological study of peritonitis among children and factors predicting mortality at a tertiary referral hospital in Rwanda

Epidemiological study of peritonitis among children and factors predicting mortality at a tertiary referral hospital in Rwanda

A retrospective study of perforation peritonitis in a tertiary care hospital in Uttar Pradesh, India

Perforation Peritonitis and the Developing World

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