The late effects of cis-platinum on renal function

Long–Term Renal Outcomes after Cisplatin Treatment

“…Our findings of an initial decline in eGFR after completion of cisplatin therapy with stabilization thereafter (Figure 1) are consistent with findings of smaller studies in adults with predominantly testicular or ovarian cancer (19,20). Our study, which included a greater diversity of tumor types, supports this initial decline in eGFR.…”

Long–Term Renal Outcomes after Cisplatin Treatment

“…Our findings of an initial decline in eGFR after completion of cisplatin therapy with stabilization thereafter (Figure 1) are consistent with findings of smaller studies in adults with predominantly testicular or ovarian cancer (19,20). Our study, which included a greater diversity of tumor types, supports this initial decline in eGFR.…”

Longitudinal kidney function outcome in aging testicular cancer survivors

“…Other groups have shown a 10-30% reduction in long-term eGFR after CBCT, though with a maximum of six years of follow-up and without a comparison group from the general population (Table 3) [35,39,[43][44][45][46][47]. Our longitudinal study is in line with these mainly cross-sectional studies, showing persisting and slightly increasing post-treatment kidney function decline dependent on treatment burden.…”

Long-Term Renal Effect of Cisplatin in Man

“…These data were confirmed by other investigators who found a decrease of GFR ranging from 12 to 38% [11][12][13]. The ERPF, which was also evaluated in two studies [ 14,15], was found to be decreased by 10 and 22%, respectively.…”

Long–Term Renal Outcomes after Cisplatin Treatment

“…Our findings of an initial decline in eGFR after completion of cisplatin therapy with stabilization thereafter (Figure 1) are consistent with findings of smaller studies in adults with predominantly testicular or ovarian cancer (19,20). Our study, which included a greater diversity of tumor types, supports this initial decline in eGFR.…”

Longitudinal kidney function outcome in aging testicular cancer survivors

“…Other groups have shown a 10-30% reduction in long-term eGFR after CBCT, though with a maximum of six years of follow-up and without a comparison group from the general population (Table 3) [35,39,[43][44][45][46][47]. Our longitudinal study is in line with these mainly cross-sectional studies, showing persisting and slightly increasing post-treatment kidney function decline dependent on treatment burden.…”

Long-Term Renal Effect of Cisplatin in Man

“…These data were confirmed by other investigators who found a decrease of GFR ranging from 12 to 38% [11][12][13]. The ERPF, which was also evaluated in two studies [ 14,15], was found to be decreased by 10 and 22%, respectively.…”

Long–Term Renal Outcomes after Cisplatin Treatment

“…Our findings of an initial decline in eGFR after completion of cisplatin therapy with stabilization thereafter (Figure 1) are consistent with findings of smaller studies in adults with predominantly testicular or ovarian cancer (19,20). Our study, which included a greater diversity of tumor types, supports this initial decline in eGFR.…”

Longitudinal kidney function outcome in aging testicular cancer survivors

“…Other groups have shown a 10-30% reduction in long-term eGFR after CBCT, though with a maximum of six years of follow-up and without a comparison group from the general population (Table 3) [35,39,[43][44][45][46][47]. Our longitudinal study is in line with these mainly cross-sectional studies, showing persisting and slightly increasing post-treatment kidney function decline dependent on treatment burden.…”

Long-Term Renal Effect of Cisplatin in Man

“…These data were confirmed by other investigators who found a decrease of GFR ranging from 12 to 38% [11][12][13]. The ERPF, which was also evaluated in two studies [ 14,15], was found to be decreased by 10 and 22%, respectively.…”