The Jiangtang Tongmai Prescription Inhibits Inflammation and Fibrosis
of Lung Fibroblast Autophagy Induced by Hyperglycemia by Regulating
CAV1 Expression
Nian Ding,
Yanbo Fan,
Chenghong Zheng
Abstract:Objective:
The lung is one of the target organs of diabetes. This study aimed to probe the protective mechanism of Jiangtang Tongmai Prescription (JTTMP) against diabetic lung injury.
Methods:
JTTMP-containing serum was collected, and a high glucose and high-fat diabetic cell model was established. The cells were treated with a drug-containing serum or a CAV1-associated vector. Transfection efficiency was measured by qRT-PCR and western blot, the cell proliferative capacity was tested by CCK-8 assay, and the… Show more
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