volume 10, issue 3, P155-162 2001
DOI: 10.1080/09629350123956
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Damir Muhvic, Volker El-Samalouti, Hans-Dieter Flad, Biserka Radoševic-Stašic, Daniel Rukavina

Abstract: BACKGROUND: Cell-wall components of Gram-positive and Gram-negative bacteria induce the production of cytokines in human peripheral blood mononuclear cells. These cytokines are the main mediators of local or systemic inflammatory reaction that can contribute to the development of innate immunity. AIMS: This study was performed to analyze the involvement of CD14 molecule in the activation of human monocytes by peptidoglycan monomer (PGM) obtained by biosynthesis from culture fluid of penicillin-treated Brevibac…

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