The Influence of Carboxytherapy on Scar Reduction

Abstract

Introduction Although it is not a new method, a carboxytherapy, which is based on intradermal or subcutaneous administration of controlled doses of CO2, is gaining more and more recognition among aesthetic medicine doctors, dermatologists and cosmetologists around the world. The consequence of applying carbon dioxide directly into tissues is associated with an immediate expansion of blood vessels, improvement of local blood supply, and, thus, tissue metabolism. It does also support natural regenerative processes. Oxygen and growth factors released from blood, within the area which undergoes treatment, stimulate fibroblasts to produce collagen and formation of new blood vessels also known as neovascularization. In addition to biochemical mechanisms, CO2 injection into the dermis or subcutaneous tissue leads to a mechanical effect exerted by pressure and flow of CO2 which is injected. It is of particular importance in scar treatments. Methods Twelve mature scars were subjected to the carboxytherapy which was performed in people aged 23–45 years. A small amount of heated, medical CO2 was injected till the moment a scar turns white. The applied flow rate equalled 100 mL/min (cc/min). Before and after a series of four treatments, the level of hydration, elasticity and colour of the skin were measured. A structured-light 3D scanner was used to determine an exact morphology of the examined scars. The 3D scanning device is seen as a sensitive and precise method of qualitative and quantitative assessment of a morphology of scars. Results The results of the measurements performed showed a reduction in the surface of the analyzed changes, as well as proved the ability of CO2 to rebuild collagen fibres. The decrease in value of parameters, which have been obtained thanks to the kutometric examination, indicates softening and loosening of connective tissue. It does confirm the effectiveness of carboxytherapy.

O Uso Da Técnica De Microagulhamento No Tratamento De Cicatrizes De Acne: Uma Revisão Literária

“…O oxigênio e os fatores de crescimento liberados do sangue, dentro da área que passa pelo tratamento, estimulam os fibroblastos a produzirem colágeno e a formação de novos vasos sanguíneos, também conhecidos como neovascularização. Além dos mecanismos bioquímicos, a injeção de CO2 na derme ou tecido subcutâneo leva a um efeito mecânico exercido pela pressão e fluxo de CO2 que é injetado (Stolecka-Warzecha et al, 2022).…”

The role of the beautician in reducing striae

“…The first therapy was used in 1932 in Royat Spa by French doctors for people with venous insufficiency. More recently, treatments with carboxytherapy have been used to stimulate the growth of collagen and elastin, reduce fatty tissue, treat scars and striae, eliminate wrinkles, and solve many other skin problems 34–37 …”

Versatile Application of Carboxytherapy in Medicine

“…Вуглекислий газ є метаболічним продуктом, який впливає на різні клітинні процеси організму, включаючи дихання, спорідненість гемоглобіну до кисню, регулювання pH крові та кислотного балансу [42]. Крім того, він має потужну антигіпоксичну, антиоксидантну, протизапальну та імунологічну дії.…”

“…Наявність в крові і тканинах Са 2+ , Na + , K + і розщеплення вугільної кислоти на Н + і НСО -3 сприяє утворенню гідрокарбонатів натрію, калію і кальцію (NaHCO 3 , KHCO 3 , Ca(HCO 3 ) 2 . Тому в організмі більша частина СО 2 знаходиться в хімічно зв'язаному виді, утворюючи бікарбонати: в плазмі -NaHCO 3 , в еритроцитах -KHCO 3 , і в кістках Ca(HCO 3 ) 2 [25,42]. В організмі CO 2 в основному переноситься кров'ю у вигляді НСО 3 у поєднанні з гемоглобіном і білками плазми.…”

“…Карбоксітерапія є ефективним методом, що дозволяє швидко і безпечно зменшити рубці [42]. Зокрема під дією СО 2 фібробласти виділяють цитокіни і фактор росту сполучної тканин, які індукують процес синтезу колагену і проліферацію клітин, що сприяє зростанню і диференціюванню кератиноцитів.…”