The Induction of Chromosomal Aberrations in Pig Kidney Cells by Far-Red Light

Gordon, Solon A.; Stroud, Agnes N.; Chen, C. H.

doi:10.2307/3573121

Cited by 10 publications

(5 citation statements)

References 30 publications

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“…One should emphasize that there is still no evidence that phytochrome is present in mammalian cells. Exposure of a monolayer of the pig kidney cells to a far red light near 750 nm was found to inhibit the incorporation of ["]thymidine into nuclei of these cells (Chen and Gordon, 1972), and to increase the incidence of the chromatoid aberrations and the number of aberrant cells (Gordon et al, 1971) with a similar dose-response maximum (5 x lo2 J/m2). Lowering the temperature of the cells during the light exposure increased the yield of aberrations (Gordon et al, 1971).…”

Section: Action On Proliferative Activitymentioning

confidence: 83%

“…Exposure of a monolayer of the pig kidney cells to a far red light near 750 nm was found to inhibit the incorporation of ["]thymidine into nuclei of these cells (Chen and Gordon, 1972), and to increase the incidence of the chromatoid aberrations and the number of aberrant cells (Gordon et al, 1971) with a similar dose-response maximum (5 x lo2 J/m2). Lowering the temperature of the cells during the light exposure increased the yield of aberrations (Gordon et al, 1971). When the cells were exposed to far red light (A = 750 nm) at various times after subculture, they showed peaks in the aberration yield when the intervals were about 16 and 22 h. These maxima corresponded to the early S-and G2-stages of the cell cycle.…”

Section: Action On Proliferative Activitymentioning

confidence: 83%

“…Irradiation of pig kidney cells with far-red light at 750 nm caused maximal yield of chromosome aberration when the synchronized population was irradiated in early S-and G2-stages of the cellular cycle (Gordon et al, 1971).…”

Section: Which Point In the Cell Cycle Is Affected?mentioning

confidence: 99%

“…Far red light, near 750 nm in wavelength, was used by Gordon et al (1971) and Chen and Gordon (1972). The interest of the authors in this particular wavelength was connected with studies on the biological role of the phytochrome.…”

Section: Action On Proliferative Activitymentioning

confidence: 99%

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Effects of Visible Radiation on Cultured Cells

Karu

1990

Photochem & Photobiology

170

118

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Section: Action On Proliferative Activitymentioning

confidence: 83%

Section: Action On Proliferative Activitymentioning

confidence: 83%

Section: Which Point In the Cell Cycle Is Affected?mentioning

confidence: 99%

Section: Action On Proliferative Activitymentioning

confidence: 99%

See 2 more Smart Citations

Effects of Visible Radiation on Cultured Cells

Karu

1990

Photochem & Photobiology

170

118

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“…Fluorescent-light induced lengthening of generation time in Astasia longa, a colorless euglenoid flagellate, was more pronounced at 20 C than at 30 C (Cook, 1968). Similarly, far-red-induced chromatid aberrations in pig kidney cells were increased by lowering the temperature of the cells during exposure (Gordon, Stroud, and Chen, 1971), and E. coli cells exposed to near-UV radiation were better able to survive if growth immediately after irradiation occurred at 30 C rather than at lower temperatures (Peak, 1970). The reason for these effects is not known.…”

mentioning

confidence: 93%

Effects of Near Ultraviolet and Visible Radiations on Cell Cycle Kinetics in Excised Root Meristems of Pisum Sativum

Brown¹,

Klein²

1973

American J of Botany

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Near‐ultraviolet and visible radiations increased the duration of the mitotic cycle in excised pea root meristems primarily by lengthening the duration of the pre‐DNA synthetic period (G1). All radiations tested shortened the duration of the post‐DNA synthetic period (G2). The most pronounced effects were exhibited by green radiation, which lengthened the duration of the cell cycle, G1, DNA synthesis (S), and mitosis (M), and shortened the duration of G2. Progression of cells arrested by starvation in G1 and G2 into DNA synthesis and mitosis was also affected by light treatments. Green radiation appeared to arrest a group of cells in DNA synthesis as well as in G1 and G2. Meristems receiving green and near‐ultraviolet radiations exhibited the most rapid progression of G1 cells through S and G2.

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Infrared, Visible and Ultraviolet Radiation

Bitran¹,

Murray²

2001

Patty's Toxicology

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Sir William Herschel's discovery of “obscure rays,” extending beyond the red end of the visible spectrum, launched the exploration of the electromagnetic spectrum outside the visible range in the year 1800. The following year Johann Ritter demonstrated that invisible rays beyond the violet end of the spectrum are capable of chemical action. These three adjacent portions of the electromagnetic spectrum: infrared (IR), visible (vis), and ultraviolet (UV) are collectively known as optical radiation. Although infrared and ultraviolet radiations are invisible to the human eye, they are considered to be “optical” because they share some propagation and interaction characteristics with visible. As does the rest of the electromagnetic spectrum, optical radiation obeys the laws of electrodynamics and can be described both as electromagnetic waves and as energy corpuscles. All known electromagnetic radiations are customarily arranged monotonically according to their energy in a continuum called the electromagnetic spectrum . The electromagnetic spectrum spans many orders of magnitude in energy and, correspondingly, in frequency and wavelength. The optical radiation range is located between microwave radiation and X‐rays. The optical radiation range is composed, in order of increasing energy, of infrared, visible, and ultraviolet radiation. Although there are no sharp, well‐defined boundaries in the electromagnetic spectrum, the optical radiation range is conventionally defined as extending from 1 mm at the bottom end of the infrared to 100 nm at the upper end of the ultraviolet. The optical range is divided as follows: Ultraviolet 100–400 nm Light 380–400 to 760–780 nm Infrared 760–780 nm to 1 mm The reason for the “fuzzy” boundaries for the visible range is that they are defined by the physiological process of vision, which has some intrinsic variability. The main mechanisms that produce optical radiation are incandescence, electrical discharge, and lasing. The wavelengths in the optical radiation range have limited penetration into the human body. Therefore, the main organs affected by optical radiation are the skin and the eyes, although systemic effects have also been identified. Evolving in an environment where the sun is the main source of optical radiation, humans have developed adaptive characteristics, such as skin pigmentation, a hairy scalp, receded eyes, and aversion responses to bright lights and to excessive heat. These characteristics, however, provide only partial protection against optical radiation. Optical radiation can act on biological tissue through thermal and photochemical processes. The extent of damage depends on the intensity of the radiation, the wavelength, the exposure time, and the optical and physiological characteristics of the tissue exposed. The variability in biological effectiveness of different wavelengths (three orders of magnitude within the ultraviolet range) is particularly striking. This has led to the definition of “biologically effective” quantities, which are obtained by using a biological spectral effectiveness function. Both the eye and the skin are at risk of acute and chronic injury from optical radiation. The ocular media transmit visible and near‐infrared radiation to the retina, but most ultraviolet and far‐infrared radiation are absorbed in the cornea and the lens. The response of the skin depends strongly on its albedo and pigmentation.

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The Induction of Chromosomal Aberrations in Pig Kidney Cells by Far-Red Light

Cited by 10 publications

References 30 publications

Effects of Visible Radiation on Cultured Cells

Effects of Visible Radiation on Cultured Cells

Effects of Near Ultraviolet and Visible Radiations on Cell Cycle Kinetics in Excised Root Meristems of Pisum Sativum

Infrared, Visible and Ultraviolet Radiation

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